Give answer of 1,2,3, MCQ's 1. Which of the following statements about delto-ALA (amino amino ievulinate Synthases are FALSE? A It catalyzes the rate limiting step in the pathway of heme synthesis B. It is allosterically activated by heme C. It synthesizes delta-ALA from glycine and acetyl-CoA D. It has a decreased activity in case of vitamin 87 deficiency E. Heme influences the concentration of delta-ALA synthase in the red blood cell precursor. 2. Select the correct statements about heme degradation: A. It involves the removal of Fe2+ from heme molecule with the generation of protoporphyrin B. During heme degradation, the protoporphyrin ring is opened and CO is released C Bilirubin is conjugated with UDP glucuronic in the spleen D. The conjugated bilirubin is transported in plasma by albumin E. The stercobilin that arises by the oxidation of urobilinogen confers the characteristic color of the feces 3. Which of the following represent possible consequences of an intense hemolysis in a newborn? A An increase of unconjugated bilirubin in the blood B. Conjugated hyperbilirubinemia C. A compensatory increase of liver glucuronyl transferase activity D. A compensatory of the amount of stercobilin in the feces E The risk of brain damage
Give answer of 1,2,3, MCQ's
1. Which of the following statements about delto-ALA (amino amino ievulinate Synthases are FALSE?
A It catalyzes the rate limiting step in the pathway of heme synthesis
B. It is allosterically activated by heme
C. It synthesizes delta-ALA from glycine and acetyl-CoA
D. It has a decreased activity in case of vitamin 87 deficiency
E. Heme influences the concentration of delta-ALA synthase in the red blood cell precursor.
2. Select the correct statements about heme degradation:
A. It involves the removal of Fe2+ from heme molecule with the generation of
protoporphyrin B. During heme degradation, the protoporphyrin ring is opened and CO is released
C Bilirubin is conjugated with UDP glucuronic in the spleen
D. The conjugated bilirubin is transported in plasma by albumin
E. The stercobilin that arises by the oxidation of urobilinogen confers the characteristic color of the feces
3. Which of the following represent possible consequences of an intense hemolysis in
a newborn?
A An increase of unconjugated bilirubin in the blood
B. Conjugated hyperbilirubinemia
C. A compensatory increase of liver glucuronyl transferase activity D. A compensatory of the amount of stercobilin in the feces
E The risk of brain damage
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