A recent genome sequencing project for the bacterium Burkholderia mallei has identified a new protein with high similarity to the lysylphosphatidylglycerol flippase enzyme. A short section of the new protein sequence is shown below. TVEVNAPGDVQKALSELQQINDGRLDIRI (a) Are any reverse turns likely to be present? Explain your answer.  (b) Are any beta-strands likely to be present? Explain your answer.  (c) Are any alpha helices likely to be present? Explain your answer.  (d) Is any supersecondary structure likely to be present? Explain your answer.  (e) Identify two residues that are likely to be buried in the core of the folded protein. Explain your answer.  (f) Identify two residues that are likely to be hydrogen bonded to each other. Explain your answer.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 20QP: If an extra nucleotide is inserted in the first exon of the beta globin gene, what effect will it...
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A recent genome sequencing project for the bacterium Burkholderia mallei has identified a new
protein with high similarity to the lysylphosphatidylglycerol flippase enzyme. A short section of
the new protein sequence is shown below.
TVEVNAPGDVQKALSELQQINDGRLDIRI

(a) Are any reverse turns likely to be present? Explain your answer. 
(b) Are any beta-strands likely to be present? Explain your answer. 
(c) Are any alpha helices likely to be present? Explain your answer. 
(d) Is any supersecondary structure likely to be present? Explain your answer. 
(e) Identify two residues that are likely to be buried in the core of the folded protein. Explain
your answer. 
(f) Identify two residues that are likely to be hydrogen bonded to each other. Explain your
answer.

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