C-alkylation of Schiff bases: BnBr, Cat* Toluene, NaOH Ph N' Co,'Bu Product Cat* N: S,S-catalyst

Q: Provide the mechansim using curved arrows of the reaction of p-t-butyl phenol treated with acetic…

A: In the given question we have to do the Friedel craft acylation of p-t-butyl phenol with acetic…

Q: A D H,O* CH,CI H,SO, H;C B E KMNO, + + HNO, H AICI, AICI, A Cl, FeCl, F+G 7. Based on the reaction…

A: (7) (a) Structures of compounds A to H are -

Q: Show each step and the required rengent clearly in the synthesis of compound B from A (A) (8)

A: The formation of compounds [2] and [3] are shown below.

Q: 1-Propose a reasonable biosynthesis of B-eudesmol from Farnesylpyrophosphate B-Eudesmol

A:

Q: 1. The dramatic reaction below was reported in the Evans synthesis of colchicine in 1981. MeO CO₂Me…

A: Note : Acid catalyzed electrophilic aromatic substitution followed by dehydration. ( see below).

Q: 3. Propose a mechanism for the reaction on the following page: -CH3 CH3 CI+ in presense of…

A: The mechanism of the reaction is shown as:

Q: OH (a) (b) (c) NH3, NABH,CN (c) C2, H20 (b) NaOH, H20 (d) (a), H* Vork out the details of the above…

A:

Q: Explain the mechin CHs NO2 SbFs HF -> in Toulene No2 over 95.

A: At first SbF5 reacts with HF to give SbF6^- and H^+.  This H^+ is attacked by nucleophilic NO2…

Q: Br2 ОН Br

A:

Q: Match the drugs with the corresponding Phase 1 reaction that will happen appropriately with the…

A:

Q: 1) How will you describe whether any compound has been oxidized or reduced? Support your answer with…

A: Note: As per our guidelines, we are supposed to answer only one question. For other question to be…

Q: : For the following reaution 1) choo se the organic products that uill be formed and then 2)…

A: Elimination reaction: It is defined as the type of organic reaction where two substituents are…

Q: Draw the structure(s) of the major organic product(s) obtained after workup of the following…

A: The first step of the reaction is the formation of quaternary ammonium bromide by the reaction of…

Q: Diazotization of aniline first involves the formation of NO* (nitrosonium ion) by the dehydration of…

A: Given

Q: In order to synthesis 1-phenylbutan-1-ol, you started the reaction with a hydration of prop-1-ene…

A:

Q: Identify the compounds in Figure 7 that are an anhydride, amide, acyl chloride, and ester. Ph Ph Ph…

A: Anhydrides, amides, acyl chlorides and esters all are derivatives of acids.

Q: d. Use retrosynthesis approach to determine the diketone from Which you below by intramolecular…

A: In retrosynthesis approach, product is broken down into its constituted reactants from which product…

Q: CI ОН PhMgBr H3O+ EtzN, CH,Cl2 Et,0 C9H1202

A: This reaction is selective attack of  grignard reaction on least hindered site of epoxide in…

Q: Doxaprost, an orally active bronchodilator patterned after the natural prostaglandins , is…

A: Given:-            Doxaprost, an orally active bronchodilator patterned after the natural…

Q: 1. þiagram the influence of the -(C-0)OCH, group on the ring. Using narrative, explain how your…

A: DIRECTING EFFECT OF SUBSTITUENTS ON RING Substituents present on the benzene ring can be activators…

Q: 3-metyl-2-butanol react with H₂SO₄ and continue with reductive ozonolysis process. What would become…

A: Alcohol reacts with sulfuric acid to give dehydration reaction and forms alkene. The alkene gives an…

Q: 2) Scheme below shows the retrosynthesis analysis of 2-bromo-4-nitroaniline via Functional group…

A: Our desired product in the given retrosynthesis reaction is 2-bromo-4-nitroaniline.

Q: Write both products of the elimination shown. Label the major product. Explain why it is major. CH31…

A: Given reaction is elimination reaction.

Q: a. Propose an electron pushing mechanism for the conversion of o-phenylene diamine plus formic acid…

A: Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: The (+) - aureol is a natural product that has shown selective activity against certain colon and…

A: Carbocations rearrange to produce more stable carbocations. In the rearrangement of carbocation, the…

Q: Draw the mechanism of the favorable reaction of CH3CO2H and sodium ethoxide (CH3CH2O-Na+) through…

A: Bronsted-Lowry acid-base theory: The Bronsted-Lowry acid-base theory states that the acid is a…

Q: Vancomycin is an important antibiotic. It is isolated from the bacterium Streptomyces orientalis and…

A:

Q: Busulfan is a cell cycle non-specific alkylating antineoplastic agent or simply a chemotherapy drug…

A: The final product is given below -

Q: What is the configuration of the chiral center in the bromoepoxide? How do you account for the…

A: Step 1- Is a Fischer esterification to make diethyl malonate. Step 2-Protectionhydroxyl group in the…

Q: 5. Provide all the missing products (A-C) and reagent (i). Suggest retrosynthetic analysis for this.…

A:

Q: The quality of the substituent for the elimination reaction is the leaving group ability of it. Like…

A: In elimination reaction atom/ group of atoms that leave the substrate is called leaving group. Speed…

Q: 5. Give the reagent(s), conditions etc. needed to selectively protect the substrates below to the…

A:

Q: 10. Provide the product(s) based on the flow of electrons below: CH, + H-CI INTERMEDIATE cr

A: It is an example of electrophilic addition reaction

Q: Propose an electron-pushing mechanism for the following transformation. Hint: use reflux (heating)…

A: Homolytic cleavage of NBS forms the Br free radical as follows:

Q: Draw the products of the following reaction sequence. Ignore any inorganic byproducts formed. 1.…

A:

Q: (e) DMP, CH2CI2 РСС, СН2CI2 Pyridinium chlorochromate in Aco OAc -OAc methylene chloride solvent OAc…

A:

Q: MeO2C -CO2H Pd(OAc)2, IOAC O a) Acetoxylation Ob) Acetylation Oc) lodination Od) Coupling

A:

Q: NaOCH2CH3 LOCH2CH3 H3CH2CO

A: This reaction occur via intramolecular cleasion condensation reaction pathway.

Q: This compound was made from a conjugated enone using a multi-step synthesis that included a direct…

A: The enone can give an addition reaction at C=C and C=O. The addition reaction at C=O is known as a…

Q: Give the structures of A and B in the following reactions. Pay special attention to stereochemistry.…

A: m-CPBA (meta chloro per benzoic acid)--->> It is used for epoxidation of alkene and also used…

Q: Why is meta substitution the only observed product for the nitration of methyl benzoate? O The…

A: Nitration happens when one (or more) of the hydrogen atoms on the benzene ring is replaced by a…

Q: Which one of the following is not a mechanistic step in the hydrolysis of benzamide? -NH + :NH3 -OH…

A:

Q: . Label each factor involved in the reaction of a carbonyl compound as "1" (preferred or "2" (if all…

A: This the concept of the size difference between anionic species and electrophilic carbonyl carbon or…

Q: Predict the product formed when the compound shown below undergoes a reaction with MCPBA in CH,CI,.…

A:

Q: (a) Give reasons :(i) CH3—CHO is more reactive than CH3COCH3 towards HCN.(ii) 4-nitrobenzoic acid is…

A: Answer (a) Introduction: An acid is a substance which can donate H+ ions. An acidic substance has…

Q: Based on the image attached, i) explain details on the nitration reaction of methyl salicylate.…

A: Nitration :  Nitration is the substitution of nitro(NO2) group of one of the hydrogen on benzene…

Q: uestion 2 Coupling a terminal alkyne with an alkenyl halide, using a mixture of a Pd and Cu(l)…

A:

Q: 15. For each entity given in Set-1 below, bring out the unique matching entity from the list given…

A: The reduction of aldehydes and ketones to alkanes is called Wolff-Kishner reduction. It is done…

Designing a Synthesis

Organic synthesis is a branch of chemical synthesis that involves the planned construction of organic compounds/molecules from smaller units that possess functional groups. Friedrich Wöhler was the first scientist who designed the synthesis of an organic compound, urea from inorganic starting materials silver cyanate with ammonium chloride via a simple, one-step synthesis.