Consider a hypothetical metabolic pathway involving four enzymes to convert molecule A into molecule E: Enz 1 Enz 2 Enz 3 Enz 4 C D B Which molecule is most likely to be a feedback inhibitor that, when present in high concentrations, will reduce the flow of material through the pathway? 01) A A O2) B (3) C 04) D 05) E 6) none of these E The activity of an allosteric enzyme will be greatest when 1) the pH is optimal for the enzyme. 2) most of the enzyme molecules are in the R conformation. 3) most of the enzyme molecules are in the T conformation. 4) there are equal numbers of enzyme molecules in the R and T conformations. un puIILS What will be the effect on the structure of an allosteric enzyme if a negative allosteric effector is added to a solution of the enzyme? 1) There will be a shift in the equilibrium between the R and T forms; the amount of T will increase. 2) There will be a shift in the equilibrium between the R and T forms; the amount of R will increase. 3) The enzyme will be denatured. 4) There will be a change in the primary structure of the enzyme.

Concepts of Biology
1st Edition
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:Samantha Fowler, Rebecca Roush, James Wise
Chapter4: How Cells Obtain Energy
Section: Chapter Questions
Problem 20CTQ: Would you describe metabolic pathways as inherently wasteful or inherently economical, and why?
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Consider a hypothetical metabolic pathway involving four enzymes to convert molecule A into molecule E:
Enz, E
Enz 1
Enz 2
Enz 3
A
1) A
O2) B
Which molecule is most likely to be a feedback inhibitor that, when present in high concentrations, will reduce the flow of material
through the pathway?
3) C
04) D
B
05) E
C
D
6) none of these
The activity of an allosteric enzyme will be greatest when
1) the pH is optimal for the enzyme.
2) most of the enzyme molecules are in the R conformation.
3) most of the enzyme molecules are in the T conformation.
4) there are equal numbers of enzyme molecules in the R and T conformations.
puiss
What will be the effect on the structure of an allosteric enzyme if a negative allosteric effector is added to a solution of the enzyme?
1) There will be a shift in the equilibrium between the R and T forms; the amount of T will increase.
2) There will be a shift in the equilibrium between the R and T forms; the amount of R will increase.
3) The enzyme will be denatured.
4) There will be a change in the primary structure of the enzyme.
Transcribed Image Text:Consider a hypothetical metabolic pathway involving four enzymes to convert molecule A into molecule E: Enz, E Enz 1 Enz 2 Enz 3 A 1) A O2) B Which molecule is most likely to be a feedback inhibitor that, when present in high concentrations, will reduce the flow of material through the pathway? 3) C 04) D B 05) E C D 6) none of these The activity of an allosteric enzyme will be greatest when 1) the pH is optimal for the enzyme. 2) most of the enzyme molecules are in the R conformation. 3) most of the enzyme molecules are in the T conformation. 4) there are equal numbers of enzyme molecules in the R and T conformations. puiss What will be the effect on the structure of an allosteric enzyme if a negative allosteric effector is added to a solution of the enzyme? 1) There will be a shift in the equilibrium between the R and T forms; the amount of T will increase. 2) There will be a shift in the equilibrium between the R and T forms; the amount of R will increase. 3) The enzyme will be denatured. 4) There will be a change in the primary structure of the enzyme.
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