Describe three popular methods for silencing tumor-suppressor genes.

Q: drug that has been screened in cancer model through the generation of induced pluripotent stem…

A: induced pluripotent stem cells are the type of stem cells that are produced from the somatic cells…

Q: Give some Examples of Drugs That Specifically Target Proteins Mutated or Abnormally Expressed in…

A: Genes have the overall control on a cell. The, growth, replication, etc. of a cell is coordinated by…

Q: Explain the mechanism of Warburg effect and how it benefits cancer cells?

A: Warburg effect is a characteristic behavior shown by cancer cells in which their glucose uptake is…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Induced pluripotent stem cells (iPS) is a type of stem cell(pluripotent) in nature that is derived…

Q: Which of the following statements about tumor suppressor genes is FALSE? a) Inactivation of tumor…

A: False statement about tumor suppressor genes.

Q: Can we cure cancer by restoring the function of tumor suppressor proteins such as mutant p53 or pRb?…

A: Cell division is a process through which a cell produces two identical daughter cells. Cell division…

Q: How can researchers pinpoint the particular driver mutations most responsible for the cancer…

A: The development of cancer is an evolutionary process at the cellular level. Several mutations…

Q: Describe three common ways that tumor-suppressor genes aresilenced.

A: Tumour suppressor genes are genes that can decrease the rate of cell division and growth. In the…

Q: Why is it important to model cancer through the generation of induced pluripotent stem cells ?…

A: Genetic transformation happens when the genetic composition of an organism is transformed by the…

Q: Explain how mutations in tumor-suppressor genes can be recessive at the level of the cell but cause…

A: A tumor suppressor gene is normally a cellular gene that regulates the cell proliferation or DNA…

Q: Is there a possibility that by manipulating the microenvironment, we could disrupt the signals…

A: Mutator phenotype is seen in cancer cells. This condition is caused by mutations in genes that are…

Q: Distinguish between proto-oncogenes and tumor suppressor genes?

A: The proto-oncogenes are those genes, which promote the cell cycle and inhibit apoptosis of the…

Q: What is the difference between an oncogene and a tumor-suppressor gene? Give some examples of the…

A: Cell proliferation, cell differentiation, and cell survival are under the control of some critical…

Q: How interfered regulatory machinery results in production of tumor?

A: Eukaryotes have well-organized nucleus. prokaryotes are devoid of nuclear arrangements. genome…

Q: Define tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene…

A: Tumor-supressor genes: Tumor-suppressor genes is defined as normal genes that will slow down the…

Q: Define about Some Proto-oncogenes and Tumor-suppressor Genes ?

A: Introduction: Proto-oncogenes and tumor suppressor genes belong to cancer critical genes whose…

Q: What is the difference between an oncogene and a tumor-suppressorgene? Give two examples of each…

A: Cancer is defined as the biological disorder in which the cells undergo uncontrolled growth and cell…

Q: Compare and contrast oncogenes and tumor suppressor genes.

A: Oncogenes are those genes that have the potential to cause cancer. These genes are often mutated or…

Q: illustrate some of the molecular mechanisms leading from loss-of-function mutations in…

A: Tumor suppressing genes also known as Anti - oncogenes are the  regulatory genes which regulates…

Q: Describe, using specific examples, the differences in how a growth factor gene and a tumor…

A: When we talk about cancer, there are certain genes associated with it. Oncogenes are genes that are…

Q: Describe the differences between point mutations, chromosomal translocations, and gene amplification…

A: Cancer is a disease that is associated with the uncontrolled division of cells and invasion of…

Q: What is the difference in an oncogene and tumor suppressor gene and how can each potentially lead to…

A: Cancer is group of diseases which are characterized by abnormal and unstoppable growth of cell and…

Q: What is the working of Tumor suppressor genes ?

A: There are two types of genes that are associated with tumors: Oncogenes: These genes when directly…

Q: Normal (nonmutant) tumor-suppressor genes often functiona. as negative regulators of cell…

A: Cancer is defined as the biological disorder in which the cells undergo uncontrolled growth and cell…

Q: Compare the usual functions of proteins encoded by proto-oncogeneswith those of proteins encoded by…

A: Proteins are macromolecules formed by the long chain of amino acids. They are involved in a wide…

Q: Distinguish between proto-oncogenes and tumor-suppressor genes. To become cancer promoting, do…

A: Oncogene is a type of gene having the ability which can develop a cell to a tumor cell when…

Q: Define oncogene, proto-oncogene, and tumor-suppressor gene.

A: The most common gene in people with cancer is p53 or TP53. More than 50% of cancers involve the lost…

Q: Explain the difference between proto-oncogene and tumor suppressor mutations in terms of its…

A: Cancer is a medical condition that is characterized by the growth of tumors in the body of an…

Q: Which type of mutation would NOT be involved in the inactivation of a tumor suppressor gene?

A: Normal cell growth in body is controlled by -  1. Protooncogene or cellular oncogene - Protooncogene…

Q: Classify the following genes as proto-oncogenes or tumor-suppressor genes: p53, ras, Bcl-2,…

A: Proto-oncogene is a normal gene which have many different functions in the cell, like providing…

Q: What role do cell check points have in cancer ?

A: Cancer is a disease that is associated with uncontrolled division of cells and invasion of…

Q: Explain in general what is meant by a proto-oncogene and how they are involved in the formation of a…

A: Proto-oncogenes are a bunch of normal genes present in a cell. They have the necessary information…

Q: Which of the following is not an example of tumor-suppressor gene? A. p53 gene B. Rb…

A: p53 gene It is a tumor suppressor gene It's activity stops the formation of tumors It is located…

Q: Apart from p53, mention and describe the function of three tumor suppressor genes you know

A: The cancer related genes can be divided into two broad categories like the proto-oncogenes and tumor…

Q: Which of the following statements correctly describes a characteristic of tumor-suppressor gene? a)…

A: Cells that progress through the cell cycle unchecked may sequentially develop malignant tumors.…

Q: What is a tumor suppressor? What is an oncogene?

A: Cancer is a diseased condition where the cells show abnormal growth and proliferation. The cancerous…

Q: Tissues and differentiation a)Explain what is meant by termination and differentiation ).b) Explain…

A: The question has been assumed to be "a)Explain what is meant by determination and…

Q: n of tu

A: Tumour suppressor genes can be defined as the gene that is involved in the regulation and…

Q: Compare and contrast oncogenes versus tumor-suppressorgenes.

A: Cancer is the uncontrolled proliferation of cells that can be treated by chemotherapy and…

Q: Explain Mutations in tumor-suppressor genes are recessive at the cellular level but dominant at the…

A: Cancer is a group of diseases involving abnormal growth of cells, which tend to proliferate in an…

Q: Would a drug that induced apoptosis or one that induced necrosis be preferable for treatment of…

A: INTRODUCTION Flowcytometry Flowcytometry is a technique that simultaneously measures and analyse…

Q: What are the key steps of transformation, tumorigenesis and metastasis on a cellular and tissue…

A: Transformation is a process in which a normal cell is transform into a cancerous cell  Tumor genesis…

Q: Explain the difference between a proto-oncogene and a tumor-suppressor gene.

A: Cancer is the state of uncontrolled cell division.

Q: Discuss the challenges of producing anticancer drugs that counteract the effects of mutations in…

A: Tumor suppressor genes are the genes that decline the cell division process, acts in programmed cell…