Give some Examples of Drugs That Specifically Target Proteins Mutated or Abnormally Expressed in Cancer Cells ?

Q: drug that has been screened in cancer model through the generation of induced pluripotent stem…

A: induced pluripotent stem cells are the type of stem cells that are produced from the somatic cells…

Q: Explain the mechanism of Warburg effect and how it benefits cancer cells?

A: Warburg effect is a characteristic behavior shown by cancer cells in which their glucose uptake is…

Q: Define tumor-suppressor genes. Why is a mutated single copy of a tumor-suppressor gene expected to…

A: The repeated and uncontrollable division of cells forms a large mass called the tumor. Tumors might…

Q: How do you target loss-of-function in cancer cells using innovative therapeutics?

A: Cancer causes millions of deaths globally. Even though progress has been done in medicine, there are…

Q: hallmarks of tumor cells

A: Introduction:-The hallmarks constitutes an organizing principle for rationalising the complexities…

Q: Cancer-promoting mutations are likely to have different effects on the activity of proteins encoded…

A: Cancer is the unnatural and excessive proliferation of cells that becomes harmful to normal body…

Q: Explain the mechanism of Warburg effect and how it benefits cancer cells

A: The question is based on Warburg effect.

Q: Describe three common ways that tumor-suppressor genes aresilenced.

A: Tumour suppressor genes are genes that can decrease the rate of cell division and growth. In the…

Q: For many years, targeted therapies for cancer treatment continue to be developed, however more and…

A: Targeted therapy is a type of cancer treatment that uses drugs designed to "target" cancer cells…

Q: Explain how genetics and epigenetics play a role in cancer.

A: Genomic precariousness, which happens through both hereditary components (basic inheritable…

Q: Describe in detail the relevance of apoptosis to cancer therapy

A: Apoptosis or programmed cell death  It is a highly regulated process that allows a cell to self…

Q: Explain the role of epigenetic alterations in cancer ?

A: Genes are the hereditary unit in an organism and are passed on from the parental generation to the…

Q: Explain how mutations in oncogenes and in tumor suppressorgenes cause cancer.

A: Cancer is a group of diseases that involves abnormal growth of the cell. These cells have the…

Q: Describe three popular methods for silencing tumor-suppressor genes.

A: Introduction Tumor suppressor genes are those that slow down the division and development of cells.…

Q: How does constitutively active Ras promote cancer?

A: In physiology carcinogenesis is known as the production of cancerous cells or tumor cells by…

Q: Describe the roles of proto-oncogenes and tumor suppressor genes in controlling cell growth, and…

A: Oncogenesis is the process of inducing cancer in the body due to mutation in the genes. Oncogenes…

Q: What is the difference between an oncogene and a tumor-suppressorgene? Give two examples of each…

A: Cancer is defined as the biological disorder in which the cells undergo uncontrolled growth and cell…

Q: Compare and contrast oncogenes and tumor suppressor genes.

A: Oncogenes are those genes that have the potential to cause cancer. These genes are often mutated or…

Q: illustrate some of the molecular mechanisms leading from loss-of-function mutations in…

A: Tumor suppressing genes also known as Anti - oncogenes are the  regulatory genes which regulates…

Q: Describe the differences between point mutations, chromosomal translocations, and gene amplification…

A: Cancer is a disease that is associated with the uncontrolled division of cells and invasion of…

Q: Based on the data presented above, propose a molecular mechanism by which indibulin is active…

A: Indibulin is known as a small synthetic molecule. This compound is novel and is known to be orally…

Q: Compare the usual functions of proteins encoded by proto-oncogeneswith those of proteins encoded by…

A: Proteins are macromolecules formed by the long chain of amino acids. They are involved in a wide…

Q: Use an example to describe tumor suppressors

A: Cancer is the state of uncontrolled cell division that has some genetic factors.

Q: Describe how mutations in genome maintenance factors promote tumorigenesis. Why would inactivation…

A: The cells are basic units of life. When any mutation in the gene takes place due to any radiation or…

Q: Explain the role of viruses in cancer initiation

A: Viruses replicate their DNA or RNA only in the host body. There are many viruses like Epstein-Barr…

Q: relationship that may exist between mutations and cancer

A: Any permanent change occurring in the DNA base sequence is referred to as a mutation. The mutation…

Q: Describe the effects of the mutation causing the p21 promoter to no longer bind p53 on cell…

A: p53 is a tumor suppressor gene but if p53 gets mutated then this protein is not able to bind to the…

Q: Explain why many oncogenic viruses contain genes whose products interact with tumor-suppressor…

A: Viruses are infectious agents. They can only replicate inside the living cells. Viruses can infect…

Q: would directly target the ability of cancer cells to evade cell growth suppressors? (evading the…

A: What is VEGF? Many cells generate vascular endothelial growth factor (VEGF), formerly known as…

Q: What role do cell check points have in cancer ?

A: Cancer is a disease that is associated with uncontrolled division of cells and invasion of…

Q: Please distinguish driver and passenger mutations in cancer.

A: Driver mutations: Mutations in known oncogenes that help cells establish or maintain the transformed…

Q: compare and contrast cancer caused by viruses and cancer caused by oncogenes

A: Introduction Cancer is a disease occurs due to uncontrolled mitosis. Cancerous cells can destroy…

Q: Explain in general what is meant by a proto-oncogene and how they are involved in the formation of a…

A: Proto-oncogenes are a bunch of normal genes present in a cell. They have the necessary information…

Q: Give examples of how mutations in signaling proteins can result in cancer

A: Mutations are a genetic phenomenon in which alterations in the sequence of nucleotides of DNA occur.…

Q: Explain how epigenetic changes can contribute to tumorigenesis.

A: Tumors are clumps of cells formed by uncontrollable cell division. Tumorigenesis is the uncontrolled…

Q: Describe the molecular mechanisms involved in P53’s role as a tumor repressor protein

A:

Q: What were the key findings after modeling cancer through the generation of induced pluripotent stem…

A: The genetic information can be stored in the form of DNA, which may be converted into functional…

Q: Tissues and differentiation a)Explain what is meant by termination and differentiation ).b) Explain…

A: The question has been assumed to be "a)Explain what is meant by determination and…

Q: Why Nutlin may represent a potential anti-cancer drug?

A: When there is DNA damage or growth factor deprivation or oxygen deficiency in a cell, it induced…

Q: Compare and contrast oncogenes versus tumor-suppressorgenes.

A: Cancer is the uncontrolled proliferation of cells that can be treated by chemotherapy and…

Q: Proto-oncogenes normally function to increase v cell division. If a mutation occurs to a…

A: Proto - oncogenes normally function to stimulating cell division . If a mutation occurs to a proto -…

Q: Explain Mutations in tumor-suppressor genes are recessive at the cellular level but dominant at the…

A: Cancer is a group of diseases involving abnormal growth of cells, which tend to proliferate in an…

Q: Please give information and explain the modeling of cancer with IPS cells (induced pluripotent stem…

A: The discovery of iPS cells opens up a wide spectrum of possible future applications including…

Q: Imagine you have used cBioportal and breast cancer patient datasets and identified a…

A: Introduction :- Cancer is defined as the uncontrolled and un-regulated proliferation of cells , due…

Q: Explain the difference between a proto-oncogene and a tumor-suppressor gene.

A: Cancer is the state of uncontrolled cell division.

Q: Discuss the challenges of producing anticancer drugs that counteract the effects of mutations in…

A: Tumor suppressor genes are the genes that decline the cell division process, acts in programmed cell…

Cancer Therapy