8 Type I Dlabetics lack insulin. Which of the following features do you expect in a tyhep I diabetic patient? Analyze carefully this figure and select the right answer.DietarycarbohydrateHigh bloodglucoseLow bloodglucoseFattyacyl-CoAFatty acyl- COASHcarnitine1 Insulin1 GlucagoncarnitineacyltransferaseCarnitineACCInactiveFattyacyl-CoAFADHphosphataseO PKAFatty acyl-carnitinePACCGlucose-Acetyl-CoA Malonyl CoAexidationlycolysis.pyruvatedebrydrogenasecomplexNADHmultistepFatty acidsAcetyl-CoAFatty acidsynthesisFatty acidBoxidationMitochondrionNo insulin, no active ACC, no malonylCoA, decreased Boxidation (burning fats), thin bodyNo insulin, active ACC, more malonylCoA, decreased Boxidation (burning fats), fat bodyNo insulin, no active ACC, no malonyICoA, excess Boxidation (burning fats), thin bodyNo insulin, no active ACC, excess malonylCoA, excess Boxidation (burning fats), fat bodyO O O O

Introduction: As mentioned there is no production of Insulin, so the person is suffering from…

Dietary carbohydrate High blood glucose Low blood glucose Fatty acyl-CaA Fatty acyl- CoASH carnitine 1 Insulin 1Glucagon caitine ACC trinderae Carnitine Fatty acyl-Can Inactive Fatty acyl- carnitine phosphatase PKA ACC FADH Glucose Acetyl-CoA Malonyl-CoA idatin ycolysi ruvate delydrogenae NADH Fatty acids Acetyl-CoA Fatty acid synthesis Fatty acid Boxidation Mitochondrion

Dietary carbohydrate High blood glucose Low blood glucose Fatty acyl-CaA Fatty acyl- CoASH carnitine 1 Insulin 1Glucagon caitine ACC trinderae Carnitine Fatty acyl-Can Inactive Fatty acyl- carnitine phosphatase PKA ACC FADH Glucose Acetyl-CoA Malonyl-CoA idatin ycolysi ruvate delydrogenae NADH Fatty acids Acetyl-CoA Fatty acid synthesis Fatty acid Boxidation Mitochondrion

Anatomy & Physiology

1st Edition

ISBN:9781938168130

Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Chapter17: The Endocrine System

Section: Chapter Questions

Problem 31RQ: Which of the following statements about insulin is true? Insulin acts as a transport protein, cany...

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Which of the following statements about insulin is true? Insulin acts as a transport protein, cany in g glucose across the cell membrane. Insulin facilitates the movement of inti acellular glucose transporters to the cell membrane. Insulin stimulates the breakdown of stored glycogen into glucose. Insulin stimulates the kidneys to reabsorb glucose into the bloodstream.
What is typically seen with biguanide use?A. Increased glucose uptake by muscle tissueA. Decreased basal insulin levelB. Decreased intestinal glucose absorption C. Gastrointestinal disturbancesD. Decreased lactate level
Patient T., 26 y/o, is in the intensive care unit with a ketoacidotic coma. Her consciousness is clouded, eye ball tone is lowered, arterial pressure - 90/60, pulse - 130 beats/minute, glycemia -35 mmol/l, PH - 7.1. The content of ketone bodies is 18 mg %. How would you manage this patients? A. Introducing 10-20 units of insulin at first by stream infusion and then by drip infusion during 1 hour by 0.05-0.1 units/kg/hour till the termination of ketoacidosisB. Introducing 500ml 5% glucose solutionC. Introducing 4% sodium carbonate 2.5 ml/kgD. Introducing 40 – 60 units of insulin hourlyE. Introducing 500 ml 0.9% sodium chloride
Alpha-glucosidase inhibitors are contraindicated in all of the following cases, except:A. Diabetic ketoacidosisA. Liver cirrhosisB. HypertensionC. Large abdominal herniasD. Ulcerative colitis
All of the following qualities apply to nateglinide, except:A. Short half-lifeB. Minimal risk for developing hypoglycemiaC. Metabolized by liver D. Restores early insulin secretionE. Excreted by kidneys
All of the following are true with respect to thiazolidinediones, except:A. They influence insulin resistanceB. They result in frequent episodes of hypoglycemiaC. They slow down progression of renal disease and development of hypertension.D. They decrease blood level of free fatty acids E. They improve metabolism
Name of a natural or synthetic molecule that interacts with Insulin? (please include your source(s)) Thank you in advance!
What is the most dangerous adverse effect following use of biguanides?A. Lactic acidosisB. HypoglycaemiaC. Diabetic ketoacidosisD. HyperosmolalityE. Hyperglycaemia
An adolescent is admitted to the intensive care unit with diabetic ketoacidosis. The nurse prepares a continuous insulin infusion of 100 units (U) regular insulin in 500 mL normal saline. How many units of regular insulin is in one mL of the solution?
If the normal fasting blood glucose range is 80-115 mg/dL, postprandial hyperglycemia at <140 mg/dL is normal, 8 hours after a meal. True False
Insulin is obligatory in the following states, except:A. Light course of type 2 diabetes mellitusB. Pregnancy in patients with type 2 diabetes mellitus C. Lactation in patients with type 2 diabetes mellitusD. Ketoacidosis in patients with type 2 diabetes mellitusE. Surgery in patients with type 2 diabetes mellitus
Diabetes mellitus is characterized by insufficiency of thepancreas to produce enough insulin to regulate the blood sugarlevel. In type I diabetes, the pancreas produces no insulin, andthe patient is totally dependent on insulin from an externalsource to be infused at a rate to maintain blood sugar levelsat normal levels. Hyperglycemia occurs when blood glucoselevel rises much higher than the norm (>8 mmol/L) for pro-longed periods of time; hypoglycemia occurs when the blood sugar level falls below values of 3 mmol/L. Both situations canbe deleterious to the individual’s health. The normal range ofblood sugar is between 3.8 and 5.6 mmol/L, the target rangefor a controller regulating blood sugar.A patient with type I diabetes needs your help to maintainher blood sugar within an acceptable range (3 mmol/L<glucose<8 mmol/L). She has just eaten a large meal (a disturbance) that you estimate will release glucose accord-ing toD(t)=0.5e−0.05t,wheretis in minutes andD(t)is inmmol/L –…