Explain the mode of action of transcription inhibitor metarrestin. Explain why transcription inhibitor is a good anticancer drug.

Q: describe the actions of the normal and mutated lac operon in absence of lactose.use picture if…

A: Lac operon is the consists of lac genes that code the enzymes and these enzymes are used to uptake…

Q: How might genomic information be helpful for the effective use of imatinib mesylate (Gleevec) in…

A: Imatinib mesylate is a drug used for the treatment of myeloid leukemia that is caused due to…

Q: describe the actions of the normal and mutated lac operon in absence of lactose

A: The Lac operon is a group of genes with a  single promoter. It takes place in prokaryotes(bacteria).…

Q: True or False: Reoressors regulate gene expression by helping RNA polymerase bind to the promoter.

A: Gene expression is the process by which information from a gene is used in the synthesis of a…

Q: Explain the energetics and kinetics of specific binding between DNA and the lac Repressor

A: Lac repressor (R), is one of the first discovered transcriptional regulators and is present in the…

Q: What is meant by Rho dependent and independent transcription termination. What is the differences?…

A: Termination in transcription is a point when enzyme stops adding nucleotides to the growing RNA…

Q: Describe the structure of an operon and state the role ofeach component of the operon.

A: Operon acts as a single regulated unit having one or more structural genes, promoter genes, a…

Q: In chemotherapy, what are the mechanism of action of cisplatin and alkylating agents.  Why are these…

A: Chemotherapy is a medication treatment that employs the use of potent chemicals to kill rapidly…

Q: Explain why (a) inactivation of the O2 or O3 sequence of the lac operon causes only a twofold loss…

A: An operon is defined as a group of genes that have a common promoter and regulator and also…

Q: Explain the function of reverse transcriptase.

A: Transcription is the process of the formation of RNA from the DNA template strand. The enzyme is DNA…

Q: How does the Trp operon work? A. Binding of Trp to a repressor protein allows the repressor to bind…

A: Trp operon is the cluster of genes that are responsible for synthesis pf operon

Q: Describe how an electrophoretic mobility shift assay is used to determine if a protein binds to DNA…

A: An electrophoretic mobility shift assay (EMSA) is a common affinity electrophoresis technique used…

Q: When cAMP binds to the Catabolite Activator Protein (CAP), it causes a conformational change on the…

A: The lac operon will be expressed at high levels if the following two criteria are met: Glucose must…

Q: 10. Modify the diagrams below to reflect the activation and repression of lac operon. Use arrows,…

A: Lac operon contains genes involved in metabolism. The genes are expressed only when lactose is…

Q: Resistance Gene." a) Using the diagram provided, describe where the forward and reverse primers…

A: # Here I have solved first part of the first question . Please send questions one by one in the…

Q: CHOICES: Isoniazid Rifampicin Ethambutol None of the Choices Causes more adverse effects to…

A: The correct option is Rifampicin. Rifampicin: • Causes optic neuritis. Explanation-…

Q: Describe how a superantigen such as toxic shock syndrome toxin can become lethal.

A: Toxic shock syndrome results due to the bacterial infection caused by Staphylococcus aureus. It is…

Q: Attenuation affects anabolic pathways, whereas repression affects either anabolic or catabolic…

A: Transcription is the process in which the DNA sequence of a gene is copied to create a molecule of…

Q: Match each of the following mechanisms with how it can change the levels of gene products--whether…

A: Operons are DNA segments that include groups of associated genes. They consist of a promoter region,…

Q: RNAi is currently being tested as a therapeutic tool for genetic diseases and other conditions.…

A: RNA interference or Post-Transcriptional Gene Silencing is a simple and rapid method of silencing…

Q: Explain how the Pyrococcus furiosus TrmBL1 transcriptionregulator is able to act as both an…

A: An activator is a regulator Pyrococcus furiosus substance that enhances the gene expression whereas…

Q: Describe a bacterial operon's structural advantage.

A: *NOTE: Kindly repost for other question. Dear Student as per the guidelines we are supposed to…

Q: Why it is essential to the positive stimulation of transcription of the lac operon ?

A: Lac operon includes the genes that code for the enzymes involved in lactose catabolism.

Q: Explain the importance of the proper targeting of nascent polypeptides

A: Protein targeting is the biological process by which proteins are transported to their destinations.…

Q: IPTG Absent IPTG Present B-Galactosidase Permease B- Permease Galactoßsidase + O+ z+ Y+ + IS ot z+…

A: Lac operon is the segment of DNA which consists of regulatory gene (I), promoter gene (P), operator…

Q: Explain about Formation of the RNA Polymerase II Transcription Initiation Complex ?

A: The process of transcription (synthesis of RNA from DNA) is initiated when RNA polymerase binds to…

Q: Why aren't ssb proteins necessary in transcription?

A: central dogma of molecular biology suggests the flow of biological information from dna to rna to…

Q: Contrast the structures and mobilization mechanisms ofretrotransposons and DNA transposons.

A: The DNA segments that move from one region in the genome into another region are called transposable…

Q: Determine the outcome for the lac operon genotype shown below: I*p*o°z*y /I*p*o*z°x* Assume lactose…

A: A group of genes that are transcribed under a single promoter and an operator is referred to as…

Q: Outline the operon theory using the lac operon as anexample

A: Operon consists of genes placed in sequential order. Lac operon has following genes- Regulator gene…

Q: Contrast the   mobilization mechanisms ofretrotransposons and DNA transposons.

A: Transposable elements (TEs) are the small segments of DNA that can move from one position to other…

Q: Describe the rationale behind the electrophoretic mobility shift assay.

A: Nucleic acid is serving as primary information carrying molecule in cells. There are two types of…

Q: What is the relationship between the rpoS gene and the SOS repair mechanism? Briefly explain.

A: In response to the severe DNA damage; many cells have the mechanism which enable them to synthesize…

Q: Explain how a gene knockdown reagent, such as RNAi or a morpholino, could interfere with expression…

A: Gene knockdown is a mechanism or technique that helps in the reduction of gene expression. It can…

Q: An individual carries a somatic mutation that changes a lysinecodon into a glutamic acid codon.…

A: A mutation is an alteration or change in a deoxyribonucleic acid (DNA) sequence. Mutations can…

Q: Differentiate between inducible and repressible opero

A: An operon is a group of genes that are expressed under the same promoter.

Q: For each of the growth conditions listed, what proteins would be bound to the lac operon? (Do not…

A: An operon consists of many related genes that are regulated by a common operator. The multiple genes…

Q: Explain the term inducer.

A: The process of transcriptional regulation is mediated by various types of regulatory proteins,…

Q: Predict the level of genetic activity of the lac operon as well as the status of the lac repressor…

A: Operon acts as a single regulated unit having one or more structural genes, a promoter gene, a…

Q: Discuss the two mechanisms that result in the termination of transcription - How do they differ and…

A: Transcription is a process in which RNA is synthesized with the help of the template strand of DNA…

Q: Explain why mRNA is preferred for making COVID-19 vaccines?

A: In general, a weakened or attenuated form of the pathogen is used as a vaccine to activate the…

Q: Explain the process of attenuation in the trp operon under the following conditi (i) No tryptophan…

A: Answer

Q: Discuss promoter clearance

A: The promoter clearance means that " any process associated with the transition from the start to the…

Q: In regulations demonstrated by initiation of transcription, if lactose is abundant, lactose in this…

A: The promoter is a region on the lac operon which is bounded by RNA polymerase to initiates the…

Q: Explain how alternate sigma factors can be used to initiate transcription of distinct sets of…

A: Answer: Introduction: Sigma factors is a bacterial transcription factors which can attach core RNA…

Q: Explain why inactivation of the O1 sequence of the lac operator almost completely abolishes…

A: Lac operon of the bacteria includes the structural genes that code for the enzymes involved in the…

Q: 1. State true or false, giving a brief justification: a. An enhancer is a type of regulatory…

A:

Q: a) State the functions of the subunits of RNA polymerase and describe transcription initiation.…

A: Operon system present in bacteria i.e in prokaryotes only.

Q: Define the function of reverse transcriptase.

A: The production of RNA from a DNA template strand is known as transcription. Because it forms RNA…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.