During an SAR effort to identify tyrosine kinase inhibitors, it was found that compound 2 was significantly more potent and selective than compound 1. To what might you attribute this improvement in activity and selectivity? Explain. ICS micromolar IC- 0.1 mcromelar

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A: V0 versus [S] : Michaelis menten kinetics 1/Vo versus 1/[S] : Lineweaver burk plot

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Pharmacokinetics

Pharmacokinetics is made up of two words: pharmakon means drug, and kinetics which means moving. Pharmacokinetics could be defined in simple words as the movement of drugs through the whole body and out of the body.