Q: Show what ester would undergo Claisen condensation to give the following B-keto ester. In your…
A: Methyl hexanoate will undergo Claisen condensation to give the beta keto ester as product. The…
Q: Which or which of the statements given below is correct. I) Maleic anhydride is a carboxylic acid…
A: (I) Maleic anhydride is a carboxylic acid derivative which on reaction with water gives the…
Q: B) Cyclopent-2-en-one to 3-oxocyclopentane carboxylic acid C) Cyclopentane to N,N-diethyl…
A:
Q: As shown below, electrophilic aromatic substitution on N,N-dimethylaniline is faster than on the…
A:
Q: soido The compound shown below is the product of a Claisen condensation Draw structural fomulas for…
A:
Q: 1) How will you describe whether any compound has been oxidized or reduced? Support the answer with…
A: Hi, we are supposed to answer one question. To get the remaining questions solved please mention the…
Q: Indicate the directivity of the molecule below, and indicate if it is an 'activator' or a…
A: NO2(nitro group) is considered as an electron withdrawing group(EWG)
Q: Draw the structure of (R)-4-deuterio-2-hexyne. Propose a suitable retro-SN2 precursor of this…
A:
Q: An elimination step is involved in the synthesis of aromatic amino acids. We can also envision this…
A: Decarboxylation, which is a chemical reaction that removes a carboxylic acid group (-COOH) from a…
Q: Fill in the missing compounds in the partial retrosynthesis shown and devise a synthesis showing all…
A: Retrosynthesis: It a part of organic chemistry where deconstruction of target molecule occur to get…
Q: Write structures for the carbonyl electrophile and enolate nucleophile that react to give the aldol…
A: Aldehydes or ketones having atleast one alpha hydrogen atom when treated with dilute base undergo…
Q: Draw the alkyl bromide(s) you would use in a malonic ester synthesis of ethyl…
A: The required alkyl bromide is 1,4 dibromobutane.
Q: Complete the following retrosynthetic analysis. Supply all reagents and precursors. Parts A and B…
A: Detail forward synthesis is given below along with retrosynthetic pathway
Q: Diazotization of aniline first involves the formation of NO* (nitrosonium ion) by the dehydration of…
A: Given
Q: 1-ethoxybut-2-yne is the desired product of a synthesis. Using the principles of retrosynthetic…
A: The answer is given as follows
Q: Minor product via E1 for 2-butanol and HCl?
A: Alcohol reacts with hydrogen chloride to give substitution and elimination reactions, depending on…
Q: Show the interconversion of the functional group and where the compound disconnects (show where the…
A: Retrosynthesis is a backward process of synthesis i.e thought process of synthesis before actually…
Q: The methoxy group (-OCH3) group is considered a .... Ortho/Para Directing Activator Ortho/Para…
A: Different type of groups, when attached with benzene ring's Carbon, they either donate their…
Q: Drag and drop the appropriate reaction conditions over each arrow as appropriate. Keep in mind the…
A:
Q: How might you convert cyclopentyl carboxylic acid to N-isopropyl cyclopentylcarboxylamide? Give two…
A: Answer - Add N,N′-dicyclohexylcarbodiimide(DCC) along with Isopropyl amine, which will carry out…
Q: Electrophiles for the electrophilic aromatic substitution reactions have to be very strong to react…
A: In the presence of sulphuric acid, protonation of nitric acid occurs in the first step. Loss of…
Q: How common electron-donating and electron-withdrawinggroups affect both the rate of reaction of a…
A: The substitution of an atom or group of atom through an electrophile is termed as electrophilic…
Q: Show how propanolol can be synthesized from 1-naphthol, epichlorohydrin , and isopropylamine.
A: When isopropylamine is treated with epichlorohydrin an amino compound with an epoxide ring is…
Q: Nitric acid is a very strong oxidizing agent. Can it possibly oxidize the starting substituent to a…
A: Nitric acid is an Oxidising agent. It provides nascent oxygen for oxidation. It oxidise primary…
Q: Like other strong nucleophiles, triphenylphosphine attacks and opens epoxides. The initial product…
A: Mechanism for the above reaction is,
Q: Using curved arrows, provide the mechanism illustrating the deprotonation performed in the previous…
A:
Q: If your product from this experiment (benzimidazole) is treated with a strong base (nBuLi) followed…
A: Benzimidazole is a fused ring in which benzene and imidazole are fused together. It is a…
Q: Nucleophilic aromatic substitution involves the formation of a resonance-stabilized carbanion…
A:
Q: Propose a multi-step synthesis for converting 1-methylcyclohexene to racemic 6-hydroxyheptanoic acid…
A: The mechanism of this reaction is hereby attached .
Q: Shown here are the resonance contributors for the cationic intermediate in the electrophilic…
A: Given,
Q: Using your knowledge of general chemistry and organic chemistry, answer the following questions:…
A:
Q: of a proton in a slow, rate-limiting step gives an anion which then expels the leaving group from…
A: Here we are required to draw the arrow to show the mechanism for the reaction The given reaction…
Q: 2. Previously, in reactions that form carbonations we could not clearly predict if SN1 or El would…
A: For a nucleophile to be strong and reactive, its conjugate base must be stable. Out of the given…
Q: Enolates are formed by deprotonation of an α-carbon hydrogen. Answer the following questions about…
A: in this given molecule alpha carbon is adjacent carbon of carbonyl group, that is at the ring…
Q: According to the reactions studied thus far in this course, ketones are able to be the substrate of…
A: Given: Ketone can act as a substrate for both oxidation as well as reduction Reaction. To find:…
Q: At pH = 12, the rate of hydrolysis of ester A is greater than the rate of hydrolysis of ester B. At…
A: The rate of hydrolysis of ester A is greater than that of the rate of hydrolysis of ester B at…
Q: Which of the following is a correct statement regarding electrophilic aromatic substitution? A.…
A: Aromatic electrophilic substitution reaction: Aromatic electrophilic substitution reactions is the…
Q: Provide a plausible arrow pushing mechanism for the reaction below. Note that the starting material…
A: The given reaction is diazotisation reaction. In this reaction a diazonium salt is formed as a…
Q: Hi, I need help to perform a retrosynthetic analysis and then to design a synthesis plan. Can you…
A: ****FGI stands for functional group interconversion****
Q: What is the difference of using toluene, hexane, and dichloromethane as solvents in SN2 reactions?…
A:
Q: 13. Which acid in each pair below is the stronger acid? Please explain your answer with the…
A: Among 2-dibromoacetic acid and bromoacetic acid, 2-dibromoacetic acid is more acidic. Because,…
Q: Provide a plausible arrow pushing mechanism for the reaction below. You may abbreviate the…
A:
Q: For the following conceptual problems, provide written responses with your selection of the molecule…
A:
Q: I would like some help finding the detailed arrow reaction mechanism for the ethylidene cyclopentane…
A: Alcohols undergo dehydration reactions in the presence of sulfuric acid followed by heat. The…
Q: Unlike alcohols which are very unreactive owing to the inability of the hydroxyl to break away on…
A: To fill the blanks with the appropriate choices.
Q: How does the negative inductive effect (−I) of chlorine in the ortho position of the phenol, reduce…
A:
Q: Explain why a diazonium group on a benzene ring cannot be used to direct an incoming substituent to…
A: Generally, the electron withdrawing substituent present in benzene ring can direct an incoming…
In benzoic acid, when it has a deactivating group in position "para" (relative to carboxylate position) , it attracts electrons towards it, weakening the acid and an activator pushes the electrons making the acid stronger.
What happens to this benzoic acid if it has a substituent at the "meta" or "ortho" position as an activator or a deactivator?
I need an explanation of what happens in each case please
Step by step
Solved in 3 steps with 2 images
- Alcohols react with sulfonyl chlorides to form sulfonate esters. Only the O-H bond of the alcohol is broken in the reaction, and so no inversion of configuration occurs. The resulting sulfonate esters are reactive in SN1 and SN2 reactions since the sulfonate group is a very weak base and is therefore a good leaving group.Draw curved arrows to show the movement of electrons in this step of the mechanism.NO2 being a deactivating group, increase the acidic nature of alcohol, by increasing the stability of the corresponding conjugate base. True FalseThe product in this reaction is basic enough to be protonated by a dilute HCl solution. Draw the protonated species, clearly showing where protonation occurs. Draw all possible resonance structures of the conjugate acid of the product, and use these to explain why the product is so much more basic than a typical ester, like ethyl acetate.
- Using your knowledge of general chemistry and organic chemistry, answer the following questions: Predict the relative acidities within each of the following groups, then identify the conjugate bases, and finally predict their relative leaving group abilities HClO3 and HClO2 PH3 and H2S [NH4]+ and [H3O]+ Explain why the trifluoromethane sulfonate (TfO-) ion is a better leaving group than the methanesulfonate (MsO-) ion.Show the interconversion of the functional group and where the compound disconnects (show where the disconnection occurs). And show the donor synthone and acceptor synthone and the appropriate reagents for the compoundThe trimethylsilyl protecting group is easily removed in aqueous solution containing a trace of acid. Propose a mechanism for this reaction. (Note that a TBDMS protecting group is stable under these conditions because of the greater steric crowding around silicon created by the t-butyl group.)
- Enolates are formed by deprotonation of an α-carbon hydrogen. Answer the following questions about enolate formation. In the molecule shown, select the α-carbon hydrogen that would be removed to form an enolate when NaOEt is used as a base. Draw the thermodynamic enolate that results for the molecule in Part 1. Draw only the enolate resonance form that includes a formal charge on the α carbon. Be sure to indicate that formal charge as well as any lone pair of electrons in your answer.Which of the following is a correct statement regarding electrophilic aromatic substitution? A. Many suitable electrophiles are unreactive and can be stored for long periods of time prior to use. B. The carbocation intermediate will lose a proton to regain aromaticity, usually from a position other than the site of the electrophilic attack. C. Formation of the carbocation intermediate has a high activation barrier due to loss of aromaticity. D. Reformation of the aromatic ring has a low activation barrier and therefore occurs slowly. E. The carbocation intermediate has several resonance structures and is negatively charged.Enolates are formed by deprotonation of an α-carbon hydrogen. Answer the following questions about enolate formation. In the molecule shown, select the α-carbon hydrogen that would be removed to form an enolate when sodium hydroxide is used as a base. (use photo to answer this question). Then, Draw the thermodynamic enolate that results for the molecule in Part 1. Draw only the enolate resonance form that includes a formal charge on the α carbon. Be sure to indicate that formal charge as well as any lone pair of electrons in your answer.