Given that the enzyme pyruvate carboxylase converts Pyruvate into Oxaloacetate and this is an anapleurotic reaction. In the liver, what is most of the OAA converted into under these conditions? Please  explain.   1. When blood glucose levels are low and the energy charge in the cell is high.     2. When mitochondrial acetyl-CoA levels are high and the energy charge is low.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter27: Metabolic Integration And Organ Specialization
Section: Chapter Questions
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Given that the enzyme pyruvate carboxylase converts Pyruvate into Oxaloacetate and this is an anapleurotic reaction. In the liver, what is most of the OAA converted into under these conditions? Please  explain.  

1. When blood glucose levels are low and the energy charge in the cell is high.  

 

2. When mitochondrial acetyl-CoA levels are high and the energy charge is low.

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