HCI RC=N + R'OH `NHR' the Ritter reaction

Q: Draw the products formed when benzoyl chloride (C,H;COCI) is treated with each nucleophile: (a) H20,…

A: Since you are posted with multiple sub-parts. As per the rule, I am answering the first three…

Q: Explain the reactivity order of the given de/activating groups: alkyl amide bromine hydroxyl…

A: The groups which increases the density on the benzene ring and hence making it more reactive than…

Q: An organic chemist reacts 1-butanol with SOCI2 in pyridine, removes the major organic product, and…

A: In this question we have to do multiple step Reaction,

Q: Draw the alkyl bromide for reaction 2. Select Draw Rings More Erase H Br Reagents Carboxylic Acid…

A: Reactant

Q: Choose the most appropriate reagent(s) for conversion of ethyl acetate to acetamide. H OEt OCH2CH3 H…

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Q: The reaction of a nitrile with an alcohol in the presence of a strong acid forms an N-substituted…

A: a. Hydrochloric acid protonate the R'OH group. The reaction proceeds with the elimination of water…

Q: Draw the products formed when benzoyl chloride (C6H5COCl) is treated with each nucleophile: (a) H2O,…

A: a.

Q: What happened to the hydrogen labeled in green? Part [2] Addition of the nucleophile and loss of the…

A: In step 4 of the reaction, the proton transfer step is taking place.

Q: 15. What is the role of PC13 in the following reaction? Br „OH OH 1. Brz, PCI, 2. Н.о a. It converts…

A: Hell-Volhard-Zelinsky Reaction: The carboxylic acid having α-hydrogen atom on treatment with bromine…

Q: GS Q1: Show the reactants needed to make the acetal below.

A: Applying concept of deprotactation of alcohol.

Q: Devise a 4-step synthesis of the aldehyde from acetylene. 1. reagent 1 2. reagent 2 H CEC-H → H3C 3.…

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Q: R-CR R H 1 The following compound can be dassified as an acid NO to. Strong and a low pka value b.…

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Q: Synthesize the following compound from cyclohexanol using any other organic or inorganic compounds.…

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Q: 1. NaOCH3 ? 2. H3O*

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Q: Draw the products formed when benzoic anhydride [(C6H5CO)2O] is treated with each nucleophile: (a)…

A: a.

Q: f. propanoic anhydride g. cyclohexyl propanoate h. 3-methylhexanoyl chloride i.…

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Q: Question 12

A: Please find below the reaction

Q: 4. A CHEM 245 student wants to synthesize some ethylene glycol to use as antifreeze in his radiator…

A: Answer to the following questions are as follows:

Q: 2 of 2 G H un acid catalyst [H+], or pyridine, is present if needed. OH HO, CHOH OH HO AA BB DD EE…

A: In this question, we will Identify three Reagents which give final Organic Product from the starting…

Q: ČOEt 1. EtO-Na+ OEt 3. NAOH, H,O, heat EtO 4. HCI, heat 2-Carbethoxy- 4-Butanolactone…

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Q: Nicotine can be made when the following ammonium salt is treated with Na2CO3. Draw a stepwise…

A: The structure of ammonium salt, from which nicotine is prepared, shows that it contains a protonated…

Q: Upon treatment with Tollen's reagent, you would expect one of these compounds to be unreactive. OH…

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Q: NH2 HO Atenolol Tenormin® Below is a two-step reaction sequence. What are the steps in the…

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Q: OH base + H20 heat H3C H. The aldol reaction is a carbonyl condensation reaction between two…

A: The beta-hydroxy aldehyde gives an E1cB elimination reaction to give an alkene. The first step of…

Q: Primary amines can also be prepared by the reaction of an alkyl halide with azide ion, followed by…

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Q: ) What is the name of the compound below? a) 3-oxopentanoic acid b) 1-acetopentanone c)…

A: Here we have to write the IUPAC name of the following componund whose structure is given.

Q: Ме Me, Ме + Ме CI Ме

A:

Q: Im sorry but i dont understand the following: "Hi and thanks for your question! Unfortunately, per…

A: Since the N is having a + charge on it. So it will lose try to take the electrons from the N-H bond.…

Q: compounds nag tul louwest pka value 13 Iklhicn O tue following the following Ccircde your angwer) ?…

A: I will explain you in details for first Question ( Question number 13 )  In this question, you want…

Q: Nicotine can be made when the attached ammonium salt is treated withNa2CO3. Draw a stepwise…

A: The first step involves slow dissociation of sodium carbonate as a base. The first step involves the…

Q: a. Propose a mechanism for the reaction of acetic anhydride with water.b. How does this mechanism…

A: (a) The reaction of acetic anhydride and water produces two moles of acetic acid. The nucleophile…

Q: Which of the following methods does not work to synthesize benzoic acid? CrO3, H2SO4, H,O A)…

A: Benzoic acid is a derivative of benzene containing -COOH functional group. It is usually prepared by…

Q: 25.ldentify the reagent that best completes the following reaction. HO d. H3PO4 a. NaOH e. HBr b.…

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Q: A) Grignard reagents are prepared from elemental magnesium and an alkyl halide. B) Grignard reagents…

A: Note: Since you have posted a question with multiple sub-parts, we will solve the first three…

Q: Q 6(a) Describe the use of protecting groups in organic synthesis, with particular emphasis on the…

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Q: 1. What reagent will be used for this reaction? ??? ОН ОН 2. What is the needed carboxylic acid to…

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Q: Nicotine can be made when the following ammonium salt is treated with Na2CO3. Draw a stepwise…

A: The structure of ammonium salt, from which nicotine is prepared, shows that it contains a protonated…

Q: Give two Friedel–Crafts acylation reactions that could be used to prepare 4-methoxybenzophenone. One…

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Q: 1. 0.5 equiv. NaOEt/EtOH 2. Mild H30* 3. 1.0 equiv. NaOEt/NAOH 4. Br 5. NaOH, H2O 6. Mild H30* ? an…

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Q: A student wanted to synthesize 4-(5-methylhex-3-yn-1-yl)phenol. The student's key step was to be the…

A: The question is based on the concept of organic reactions. we have to identify the correct product…

Q: [8] Which compound when treated with acid and or heat would yield following ČH3 (a) hexanoic…

A: The given reaction is the cyclic ester formation. Cyclic esters are called lactones. Lactones are…

Q: The reaction of a nitrile with an alcohol in the presence of a strong acid forms an N-substituted…

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Q: 8) The product of Claisen condensation is a) a-keto ester b) B-keto ester c) 8-keto ester 9)…

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Q: OH - NH, Br2/KOH →product; 1. (a-hydroxy amide) Product of this Hoffmann bromamide reaction is : OH…

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Q: Which one is INCORRECT? a.Br2 : electrophilic aromatic substitution b.Neutral KMnO4 : oxidation…

A: 1.The reaction of benzene with Br2 is an example of electrophilic aromatic substitution. Bromine…

Q: Me Me OMe 9. 10

A: We are given two eater molecules:

Q: a) What two products are obtained when acetic anhydride reacts with N-isopropyl butanamine? Be sure…

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Q: Draw the products of the following reactions w given starting material 1. HCl 2. KMnO4 3. BH3…

A: We have to find out the product when 1-ethynylcyclohexane react with different reagent.  1) with HCl…

Q: Consider the following reaction schemes involving the reaction of an imine with an organolithium…

A: Non-bulky organolithiums like n-BuLi can undergo halogen exchange reaction as well as nucleophilic…

Reactions at the Alpha Carbon Atom

The position next to the ketone or aldehyde functional group is termed as alpha position and the reaction which occurs at alpha position is called alpha substitution reaction. In an alpha substitution reaction, the alpha proton atom is substituted by an electrophile by the formation of an enol intermediate or enolate ion intermediate. Most of the carbonyl compounds go through an alpha substitution reaction.