Identify what is asked Glycerol --> Glycogen Pyruvate --> Glucose Acetyl CoA --> Fats Fats-> Acetyl Co Lactate --> Glucose
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- If the brain needs glucose, then gluconeogenesis stops after reaction (9, 8, 10, 2) because (phosphoenolpyruvate, glucose, glucose-6-phosphaet, fructose-6-phosphate) can be exported from the hepatocyte using a transporter.choose the metabolic pathway being described in the statement choices: Digestion Glycolysis Formation of Acetyl CoA Krebs Cycle ETC Reactions Glycogenesis Glycogenolysis Gluconeogenesis 1. catalyzed initially by glycogen phosphorylase 2. breaking of glycosidic linkages of glycogen 3. requires pumping of hydrogen ions 4. lactic acid is converted to glucoseWhich of the following statements about the "central role" of TCA is/are correct? a. Some metabolic intermediates of TCA are used as non-carbohydrate sources for gluconeogenesis. b. β-oxidation of lipids produces acetyl-CoA that can enter TCA. c. All metabolic intermediates in TCA are used in the biosynthesis of amino acids. d. Degraded amino acids are converted to metabolic intermediates of TCA, then to ketone bodies.
- Consider the following statements: (1) the products of the first two stages of cholesterol biosynthesis are, respectively, mevalonate (C6) and isopentyl pyrophosphate (2) Over 90 percent of the total dietary lipids are triaglycerols (3) The activation stages of fatty acid oxidation involves both CoA & ATP Choices: a. Only one of the statements is true b. All three statements are true c. Two of the three statements are true d. None of the statements are trueUpon digestion of starch, isomaltose (an isomer of maltose), one of its degradation products, is further hydrolyzed into its monosaccharide components prior to intestinal absorption and entry into the glycolysis. Calculate the number of ATP molecules produced from the digestion and complete oxidation of 1 molecule of isomaltose considering the glycerol 3-phosphate shuttle. a. Total number of glucose molecules entering glycolysis: b. Total number of pyruvate molecules produced at the end of glycolysis: c. Total number of mitochondrial NADH produced after pyruvate is acted upon by the pyruvate dehydrogenase complex: d. Total number of CO2 released right after the pyruvate dehydrogenase complex reaction: e. Total number of acetyl CoA molecules entering the citric acid cycle: f. Total number of net cytosolic ATP molecules produced right after glycolysis: g. Total number of all NADH molecules produced after complete oxidation: h. Total number of all FADH2 molecules produced after…Upon digestion of starch, isomaltose (an isomer of maltose), one of its degradation products, is further hydrolyzed into its monosaccharide components prior to intestinal absorption and entry into the glycolysis. Calculate the number of ATP molecules produced from the digestion and complete oxidation of 4 molecules of isomaltose considering the glycerol 3-phosphate shuttle. a. Total number of glucose molecules entering glycolysis: b. Total number of pyruvate molecules produced at the end of glycolysis: c. Total number of mitochondrial NADH produced after pyruvate is acted upon by the pyruvate dehydrogenase complex: d. Total number of CO2 released right after the pyruvate dehydrogenase complex reaction: e. Total number of acetyl CoA molecules entering the citric acid cycle: f. Total number of net cytosolic ATP molecules produced right after glycolysis: g. Total number of all NADH molecules produced after complete oxidation: h. Total number of all FADH2 molecules produced after…
- To begin the TCA cycle, pyruvate must be converted into acetyl-Coenzyme A (acetyl-CoA) by the enzyme complex of pyruvate dehydrogenase. This complex requires 5 different coenzymes to function properly. What are they?Which of the following reactions required dihydrolipoyl dehydrogenase? Oxidative decarboxylation of pyruvate Oxidative decarboxylation of a-ketoglutarate Both A and B Neither A nor B Fatty acid biosynthesis is stimulated by: Decreased levels of citrate Increased levels of palmitoyl-CoA Increased levels epinephrine Increased levels of AMP All of the above None of the aboveWhich of the following glycolytic enzymes catalyzes the conversion of fructose-1,6-bisphosphate into the two product molecules dihydroxyacetone phosphate, and glyceraldehyde-3-phosphate? phosphoglycerate kinase pyruvate kinase malate dehydrogenase aldolase phosphofructokinase
- What is the final reaction in the final round of fatty acid synthase? Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP ReductaseCompare and contrast the following items related to lipid metabolism. Cite their main similarities/or differences. 1. Dehydrogenase enzyme vs. dehydratase enzyme(in context of lipid metabolism). 2. Steroid hormones vs. prostaglandins (in terms of their biosynthetic pathways). 3. Fatty acid synthase complex vs. pyruvate dehydrogenase complex.In type I diabetes mellitus, excessive production of acetyl-CoA may surpass the body’s capacity to oxidize it. As a result, acetoacetate, β-hydroxybutyrate, and acetone (ketone bodies) accumulate. When generated in large amounts, blood pH falls, thereby reducing the capacity of red blood cells to carry oxygen. Explain in general terms how high concentrations of ketone bodies may result in a fatal coma.