If there are multiple start condo, how can you identify the real start codon? By observing Okazaki fragments By identifying splicing site Using sequence data bases By identifying Kozak sequence Which one is not a part of the transcription unit? RNA primase Promoter RNA coding sequence Terminator

Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter13: Gene Expression
Section: Chapter Questions
Problem 8TYU: Which of the following is/are typically removed from pre-mRNA during nuclear processing in...
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  1. If there are multiple start condo, how can you identify the real start codon?
  2. By observing Okazaki fragments
  3. By identifying splicing site
  4. Using sequence data bases
  5. By identifying Kozak sequence
  6. Which one is not a part of the transcription unit?
  7. RNA primase
  8. Promoter
  9. RNA coding sequence
  10. Terminator
Expert Solution
Introduction:

Transcription and translation are specialized events that are part of the central dogma i.e. DNA to RNA to Protein.

Answer 1:

Correct Option -By identifying Kozak sequence

The Kozak sequence is a sequence that acts as the initiating sequence in eukaryotic organisms. When there are multiple start codons, this sequence is the one that marks the initiating site for translation. A part of the Kozak sequence is conserved and seen in most mRNAs with minute one or two changes beyond it. It ranges from nucleotide number -6 to +6; if +1 is assigned to adenine of the AUG (METHIONINE) codon. 

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