If acyetal-CoA dehydrogenase was unavailable, malonyl-CoA could not be made from aceytal-CoA. That would yield a glut of acetyl-CoA that could not be shuttled into fatty acid synthesis. Would acetyl-CoA then be preferentially be taken up in the TCA cycle? Beta-oxidation? or another pathway?

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter23: Fatty Acid Catabolism
Section: Chapter Questions
Problem 19P
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Question:
If acyetal-CoA dehydrogenase was
unavailable, malonyl-CoA could not be
made from aceytal-CoA. That would yield
a glut of acetyl-CoA that could not be
shuttled into fatty acid synthesis. Would
acetyl-CoA then be preferentially be taken
up in the TCA cycle? Beta-oxidation? or
another pathway?
Transcribed Image Text:Question: If acyetal-CoA dehydrogenase was unavailable, malonyl-CoA could not be made from aceytal-CoA. That would yield a glut of acetyl-CoA that could not be shuttled into fatty acid synthesis. Would acetyl-CoA then be preferentially be taken up in the TCA cycle? Beta-oxidation? or another pathway?
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