If acyetal-CoA dehydrogenase was unavailable, malonyl-CoA could not be made from aceytal-CoA. That would yield a glut of acetyl-CoA that could not be shuttled into fatty acid synthesis. Would acetyl-CoA then be preferentially be taken up in the TCA cycle? Beta-oxidation? or another pathway?
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- Question:- Two enzymes, acetate kinase and phosphotransacetylase, convert acetate [CH3C(O)O–] and ATP to acetyl phosphate and ADP (acetate kinase reaction) then acetyl phosphate and CoASH (coenzyme A) into acetyl-CoA and inorganic phosphate (Pi ; phosphotransacetylase reaction). What is the ΔG°' for the synthesis of acetyl-CoA from acetate, CoASH, and ATP by this enzyme pair?Need help, please. Given that the enzyme pyruvate carboxylase converts Pyruvate into Oxaloacetate and this is an anapleurotic reaction. In the liver, what is most of the OAA converted into under these conditions? Please explain. 1. When blood glucose levels are low and the energy charge in the cell is high. 2. When mitochondrial acetyl-CoA levels are high and the energy charge is low.Question-An individual suffers a deficiency in pancreatic amylase so that this enzyme is not normally active. What food component will this effect and how will it be affected? What functions of food processing will be affected? How will the individual's nutrition be impacted by this deficiency?
- Question:- Ketone body carbons enter the central metabolic pathways of the cells by conversion to: a. acetyl-CoA b. pyruvate c. citrate d. butyrate e. glucose-6-phosphateInstructions. Given each set of information which may include common name(s) and the reaction catalyzed, you are required to identify the main class of the specific enzyme described. Name: citryl-CoA synthetase Reaction: ATP + citrate + CoA = ADP + phosphate + (3S)-citryl-CoA Name: D-xylulose reductase Reaction: xylitol + NAD+ = D-xylulose + NADH + H+ Name: cellobiose phosphorylase Reaction: cellobiose phosphate = α-D-glucose 1-phosphate + D-glucose Name: carbonic anhydrase Reaction: H2CO3 = CO2 + H2O Other info: The enzyme catalyzes the reversible hydration of gaseous CO2 to carbonic acid, which dissociates to give hydrogencarbonate above neutral pH. Name: pantoate activating enzyme Reaction: ATP + (R)-pantoate = AMP + diphosphate + (R)-pantothenate.Question:- Explain how the total yield of ATP from the oxidation of 1 mole of glucose to CO₂ + H₂O is affected by the use of the above shuttle versus the use of the Malate Aspartate Shuttle. (above shuttle is glycerol 3-phosphate shuttle)
- BIOC 384 Citrate Cycle Regulation and Intermediates Q11.1: Explain why a mutation in pyruvate carboxylase that blocks its ability to be regulated by acetyl-CoA results in lower rates of energy conversion via the Citrate Cycle. Hint: see figure 10.36.QUESTION: How are the following enzymes involved in the anabolism of fatty acids? (please include structure, function and reactions) Acetyl co A carboxylase, Malonyl acetyl transcyclase, Hydratase, ThioesteraseQuestion:: Acyl CoA synthetase hydrolyzes ATP to AMP + PPI (pyrophosphate) as part of the activation of fatty acids to fatty acyl-CoA. Explain the role played by the enzyme inorganic pyrophosphatase in this reaction (in the activation of fatty acids to fatty acyl CoA) in the space provided below.
- Another biochemical study from another patient reveals a 100X increase in the KM value for the enzyme succinyl-CoA synthetase for this individual (only isozyme expressed). What metabolic and physiological consequences would you predict resulting from this enzymatic change?Good hand written explanation of this question Asap Thank you Illustrate the biochemical pathways for one complete cycle of b-oxidation of fatty acyl CoA (giving names and structures of intermediates, substrates and products of each reaction, and names of enzymes).Please please help me with these, thank you so muchshow the de novo synthesis of capric acid and which pathways produce NADPH? How is acetyl coA carboxylase being regulated?