(ignoring stereochemistry and possible aldol condensation products) could occ Some may be easier than others and, overall, this is likely a difficult reaction given the two ketone starting materials. a. Provide all 8 theoretically possible products for this reaction. b. How could you change the reaction conditions to favor the formation of ju one of the 8 possible products. It can be any of the products but you mus give at least one specific step that could be taken to help increase selectivity. روع NaOH

(ignoring stereochemistry and possible aldol condensation products) could occ Some may be easier than others and, overall, this is likely a difficult reaction given the two ketone starting materials. a. Provide all 8 theoretically possible products for this reaction. b. How could you change the reaction conditions to favor the formation of ju one of the 8 possible products. It can be any of the products but you mus give at least one specific step that could be taken to help increase selectivity. روع NaOH

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter26: Aldol And Claisen Reactions

Section: Chapter Questions

Problem 28CTQ

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Similar questions

1. Discuss the role of the Aldol condensation reaction in the synthesis below. What specific reaction was used in the synthesis? What is the importance of the aldol reaction in the entire synthetic approach? 2. Show the detailed reaction mechanism involved in their corresponding specific parts in this syntheses.
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Self-condensation of acetone is a possible side reaction for the aldol condensation(Reaction 1). Draw the structure of this side product. How is this side reaction minimizedin our procedure written below? Reaction 1 - Experimental Procedure: In a clean, small Erlenmeyer flask, combine your unknownaromatic aldehyde (350 μL (400 mg if it is a solid)), 95% ethanol (2.0 mL), and 5 N aqueoussodium hydroxide (0.6 mL). Swirl to mix, and then add acetone (100 μL). Stir/swirl vigorously for30 minutes, until precipitation is complete. If no precipitate forms after 15 minutes, heat theErlenmeyer flask gently in on the sand bath in the hood for 15 minutes, and then allow it to coolto room temperature. Whether heated or not, cool your Erlenmeyer flask in an ice bath for 10minutes to ensure complete crystallization. Collect the product by vacuum filtration. (If you donot have any solid at this point, evaporate all solvent in the sand bath. Recrystallize if solidresidue is obtained; otherwise stop…
1. Write the reaction that you will do this week for the Williamson ether synthesis. Label the nucleophile and the electrophile, the nucleophilic atom and the electrophilic atom. 2. Mechanistically, what type of reaction is the ether synthesis that you will perform this week? 3. An extraction is done for the work-up. What liquids will be used for the extraction? In which liquid will the product be? Will the product be in the top layer or the bottom layer?
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how do i know if my aldol condensation is E or Z with the help of IR and NMR? what peaks should i be looking at? also, can someone give me a example of how to calculate the percent yield for aldol condensation?
Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the aldol or enone below. You do not have to consider stereochemistry. Draw the enolate ion in its carbanion form. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu.
aldol condensation reaction followed by dehydration? (Please help me with this reaction) Please do it neat and clean
In a mixed aldol condensation with unknown aldehydes and ketones experiment, some aldol condensation reactions need to be heated for the dehydration step to occur. Explain why that was not necessary for the reactions carried out in this experiment? [Hint: what makes the product especially stable?]. This experiment used ethanol, acetic acid, sodium hydroxide, cyclohexanone and 4- methoxybenzaldehyde.
This is Aldol condensation 1.The protocol says that, after adding in all the reactants, stir for an additional 15 minutes. A student swirled for only 8 minutes and then, correctly, stopped and proceeded with isolating the product. What did the student do that gave such confidence and accuracy?
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True or false 1.Hydroxide is the good leaving group for SN2 reaction. 2.Iodide ion is the better leaving group than the bromide ion. 3.Ethyl bromide is the better substrate than t-butyl bromide for SN2 reactions. 4.water is the protic solvent. 5.Sn1 reactions take place in one single step.