ILLUSTRATIONS. For each of the given proteins: ● Draw the final location of the following proteins after being translocated. ● Label the organelle (as well as the organelle parts/compartments) and the cytosol (if necessary) in order to clearly depict the protein's location and orientation. ● Label the amino and carboxyl ends of the protein. ● Below your drawing, indicate: a. the receptor/s b. the energy source C. if there is signal peptide cleavage or none Endoplasmic Reticulum H₂N- signal seq -COOH retrieval signal sequence
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- BIOMOLECULES - MULTIPLE CHOICE - Please answer properly QUESTION : If a cell has an adequate supply of adenine nucleotides but requires more guanine nucleotides for protein synthesis: 1. Glutamine-PRPP amidotransferase will not be fully inhibited 2. AMP will be a feedback inhibitor of the condensation of IMP with aspartate 3. ATP will stimulate the production of GMP from IMP 4. ATP will inhibit nucleoside diphosphate reductase. Choices A. 2 and 4 B. 1 and 3 C. 1, 2, 3, and 4 D. 1, 2, and 3Tags: Biology, chemistry, biochemistry, metabolic pathway, cellular respiration, ATP synthase, alzheimer's disease It was observed that the β-subunit of the ATP synthase has a low level of expression in Alzheimer’s disease (neurodegenerative disorder). Explain a possible link between this observation and the said disease.Exponential expansion? Compare the amount of information inherent in the genome, the proteome, and the glycome.
- 5) Consider the hypothetical biochemical pathway shown below. Assume that each letter (A, B, C, etc) represents a molecule and each number over an arrow (1, 2, 3, etc) represents an enzyme that catalyzes that reaction (so enzyme 2 catalyzes the conversion of B to C). Indicate all the probable feedback inhibition interactions that would be expected to regulate the activity of enzymes in this pathway. please indicate each interaction in the format example: "X will inhibit enzyme 27".BIOMOLECULES - MULTIPLE CHOICE - Please answer properly QUESTION : In patients with Lesch Nyhan Syndrome, purine nucleotides are overproduced and over excreted. The hypoxanthine analogue Allopurinol, which effectively treats gout , has no effect on the severe neurological symptoms of Lesch- Nyhan patients because it does not? A. decrease de novo pyrimidine synthesis B. decrease de novo purine synthesis C. decrease urate synthesis D. increase PRPP levels (Phosphoribosyl pyrophosphate)1J. Please help me in detail. for molecular Mechanism of ATP versus GTP selectivity of adenylate kinase
- BIOMOLECULES - MULTIPLE CHOICE - Please answer properly QUESTION : Major controls of de novo AMP synthesis include: 1. allosteric inhibition by GMP allosteric inhibition by AMP 3. availability of PRPP 4. stimulation by GTP A. 1, 2, 3, and 4 B. 1, 2, and 3 C. 2 and 4 D. 1 and 3Choices for each phrases: a, b, y, t, v, e; gtp, cgt, atp, adp, camp, catp; gtp, gdp, atp, adp, camp, catp; histamine kinase, gaunylyl cyclamen, phosphorylation, adenylyl cyclaseBIOMOLECULES - MULTIPLE CHOICE - Please answer properly QUESTION : In human beings, what is the major control of de novo pyrimidine nucleotide synthesis? A. substrate availability B. competitive inhibition of carbamoyl phosphate synthetase II C. feedback inhibition of glutamine-PRPP amidotransferase D. vailability of N-acetyl glutamate
- 1G. Please help me in detail. For Molecular Mechanism of ATP versus GTP selectivity of adenylate kinase, Write an expression for the reaction velocity.The first step in amino acid catabolism usually involve transamination.since ammonia is a serious neurotoxin, the body maintains the nitrogen and ammonia balance carefully. Discuss the pathway, organelle and organs involved in maintaining this balance. Provide a schematic presentation of the pathway to supplement your discussion.Predict the changes in specific activity (ex. increases, decreases) and concentration of your protein as a percent of total protein in the sample from beginning (cell lysate) to the end of a protein purification scheme.