In eukaryotes the DNA replication rate is 50 nucleotides persecond. How long does the replication of a chromosome of150 million base pairs take? If eukaryotic chromosomeswere replicated like those of prokaryotes, the replication of agenome would take months. Actually, eukaryotic replicationtakes only several hours. How do eukaryotes achieve thishigh rate?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
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Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 18QP: Replication involves a period of time during which DNA is particularly susceptible to the...
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In eukaryotes the DNA replication rate is 50 nucleotides per
second. How long does the replication of a chromosome of
150 million base pairs take? If eukaryotic chromosomes
were replicated like those of prokaryotes, the replication of a
genome would take months. Actually, eukaryotic replication
takes only several hours. How do eukaryotes achieve this
high rate?

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