Which of the following statements about DNA polymerase III holoenzyme from E. coli are correct. 1. It elongates a growing DNA chain approximately 100 times faster than does DNA polymerase I. 2. It associates with the parental template, adds a few nucleotides to the growing chain, and then dissociates prior to initiating another synthesis cycle. 3. It maintains a high fidelity of replication, in part by acting in conjunction with a subunit containing a 3' -> 5' exonuclease activity. 4. When replicating DNA, it is a molecular assembly composed of at least eight different kinds of subunits.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter11: Genome Alterations: Mutation And Epigenetics
Section: Chapter Questions
Problem 18QP: Replication involves a period of time during which DNA is particularly susceptible to the...
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Which of the following statements about DNA polymerase III holoenzyme from E. coli are correct.
1. It elongates a growing DNA chain approximately 100 times faster than does DNA polymerase
I.
2. It associates with the parental template, adds a few nucleotides to the growing chain, and then
dissociates prior to initiating another synthesis cycle.
3. It maintains a high fidelity of replication, in part by acting in conjunction with a subunit
containing a 3' -> 5' exonuclease activity.
4. When replicating DNA, it is a molecular assembly composed of at least eight different kinds of
subunits.
Transcribed Image Text:Which of the following statements about DNA polymerase III holoenzyme from E. coli are correct. 1. It elongates a growing DNA chain approximately 100 times faster than does DNA polymerase I. 2. It associates with the parental template, adds a few nucleotides to the growing chain, and then dissociates prior to initiating another synthesis cycle. 3. It maintains a high fidelity of replication, in part by acting in conjunction with a subunit containing a 3' -> 5' exonuclease activity. 4. When replicating DNA, it is a molecular assembly composed of at least eight different kinds of subunits.
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