It is hypothesized that there are fluctuations in norepinephrine (NE) levels which accompany fluctuations in affect with bipolar affective disorder (manic-depressive illness). Thus, during depressive states, NE levels drop; during manic states, NE levels increase. To test this relationship, researchers measured the level of NE by measuring the metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG in micro gram per 24 hour) in the patient's urine experiencing varying levels of mania/depression. Increased levels of MHPG are correlated with increased metabolism (thus higher levels) of central nervous system NE. Levels of mania/depression were also recorded on a scale with a low score indicating increased mania and a high score increased depression. The data is provided below. MHPG Affect 980 22 1209 26 1403 8 1950 10 1814 5 1280 19 1073 26 1066 12 880 23 776 28 a. Can MHPG significantly predict affect? Please support your answer. b. Please report the regression equation and then interpret the following: i. Slope – ii. Intercept – iii. R (squared) c. Increases in MHPG cause increases in affect...true or false? Please explain.

Glencoe Algebra 1, Student Edition, 9780079039897, 0079039898, 2018

18th Edition

ISBN:9780079039897

Author:Carter

Publisher:Carter

Chapter10: Statistics

Section10.1: Measures Of Center

Problem 9PPS

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It is hypothesized that there are fluctuations in norepinephrine (NE) levels which

accompany fluctuations in affect with bipolar affective disorder (manic-depressive

illness). Thus, during depressive states, NE levels drop; during manic states, NE levels

increase. To test this relationship, researchers measured the level of NE by measuring the

metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG in micro gram per 24 hour) in the

patient's urine experiencing varying levels of mania/depression. Increased levels of

MHPG are correlated with increased metabolism (thus higher levels) of central nervous

system NE. Levels of mania/depression were also recorded on a scale with a low score

indicating increased mania and a high score increased depression. The data is provided

below.

MHPG Affect

980 22

1209 26

1403 8

1950 10

1814 5

1280 19

1073 26

1066 12

880 23

776 28

a. Can MHPG significantly predict affect? Please support your answer.

b. Please report the regression equation and then interpret the following:

i. Slope –

ii. Intercept –

iii. R (squared)

c. Increases in MHPG cause increases in affect...true or false? Please explain.

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