Mrs. Xexy Lucero, GO, 25 years old asks Nurse Zasha about pre symptomatic genetic testing for Huntington's disease. Nurse Zasha should base her response on which of the following? (Select all that apply) a. One of the parents died of Huntington's disease b. if the woman is negative for the gene, her children should be tested to see whether or not they are carriers c. Presymptomatic testing cannot predict whether or not the gene will be expressed. d. If the woman is positive for the gene Huntington's, she will develop the disease later in life e. Both parents are carriers
Q: A couple has one child with bilateral retinoblastoma. The mother is free from cancer, but the father…
A: Since you have posted a question with multiple sub-parts, we solve the first sub-part for you to get…
Q: Create a hypothetical person and situation as a real life example to illustrate your position. Who…
A: Z is a 31-year-old male and he wishes to marry. He is the only child of his parents. His fiancé B…
Q: Hemophilia is an X-linked recessive disease. A hemophilic man marries a woman who is not a carrier…
A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…
Q: In the future, gene technology may make it possible for parents to produce children with athletic…
A: Gene editing is the process by which editing of a genome is done to produce certain desired results…
Q: Huntington disease (HD) is a rare dominant condition in humans that results in a slow but…
A: Introduction :- Huntington's disease is a degenerative brain disease caused by a single faulty gene…
Q: Which pathology leads to an increased risk of Alzheimer’s disease? Select one: a. Homozygosity for…
A: Alzheimer's disease is a type of disease in which brain cells waste away. It a progressive disease…
Q: Assume that you are a genetic counsellor and analyzing RFLP pattern for a family with three…
A: RFLP is an analytical technique that uses restriction endonucleases to determine whether a…
Q: Describe how Morgan’s results deviated from Mendelian inheritance and led to the discovery of a new…
A: Linkage: Defines how two genes located on the same chromosomes (close to each other) are inherited.…
Q: The expression of antigen A or antigen B in red blood cells requires the help of an H antigen. A…
A: Given information Antigen A and antigen B in red blood cells need H antigen for expression. A…
Q: The following data were presented to a court during a paternity suit: a) the infant is a universal…
A: in humans, the ABO blood grouping is primarily used to identify a persons blood type. this grouping…
Q: Two mothers give birth to sons at the same time at a busy urban hospital. The son of mother 1 is…
A: Haemophilia is a recessive X linked trait which leads to abnormal hemorrhage from the cut site of…
Q: Fitz was found to be a carrier for the deltaF508 mutation in cystic fibrosis (autosomal recessive).…
A: Cystic fibrosis is an inherited disease that severely affects the digestive system, lungs, as well…
Q: A woman knows that her mother is a carrier of Kartagener’s syndrome (an autosomal recessive…
A:
Q: The time is coming when choosing the genetic traits of your child is going to be possible. What…
A: The two major issues with upcoming technology of genetic selection will be\ It will lead to…
Q: Duchenne muscular dystrophy is sex linked and usually affects only males. Victims of the disease…
A: Duchenne muscular dystrophy is recessive sex-linked genetic disorder that typically affects the…
Q: Marfan Syndrome is a dominant trait inheritance in humans. It is a disorder that affects the…
A: Marfan syndrome is a genetically inherited disease that is an autosomal dominant trait. It can…
Q: About 90% of your DNA are introns, or junk DNA, meaning that they do not code for proteins or shape…
A: Any nucleotide sequence within a gene that is deleted during the maturation of the final RNA product…
Q: Mrs. Xexy Lucero, GO, 25 years old has no affected genes. However, his partner Mr. Lucas Narciso, 30…
A: Genes are functional unit of DNA. DNA is the genetic material that stores genetic and hereditary…
Q: blood typing is often used as evidence in paternity cases in the court of law. In one case, the…
A: Genes are the specific codes of these amino acids which produces a protein and alleles is the…
Q: A particular person is said to be a carrier of a genetic trait. What does this tell you about their…
A: BASIC INFORMATION USED IN GENETICS HETEROZYGOUS - Every gene has two characters one being the…
Q: Trisha (mother of the baby) Charlotte (baby) Ronnie (Trisha's husband) Johnny (the grad student)…
A: I) Origin of bombay blood group is in Mumbai in 1952.
Q: The M97 allele of the BRCA1 gene is a rare autosomal dominant allele that is only 20% penetrant in…
A: Breast cancer is characterized by abnormal growth of breast tissues. Inverted nipple, change in the…
Q: b. Two couples are heterozygous for genes that cause albinism, but each gene specifies a different…
A: Disclaimer: Due to multiple sub-parts of the question, the first 3 (b, c, d) are being solved.
Q: Non-additive genetic factors make children less resemble their parents true and false (with…
A: The degree to which genetic differences account for differences in people's characteristics is…
Q: Please help True or false, if false rewrite the statement in a way that makes it true. a) A cell…
A: A cell can be defined as the basic structural, functional, and biological unit of all known living…
Q: 1.) What is the probability of Mary as a carrier of the death gene?
A: The branch of biology that deals with the study of genes, heredity and genetic variations are termed…
Q: You met with two parents whose first child has sickle cell anemia. (The parents show no signs of the…
A: The mutation in a single gene results in Mendelian disorders. There are five types of Mendelian…
Q: The world can be a scary place. There are many disease causing organisms and genetic disorders that…
A: Any disease caused by an aberration in an individual's genetic composition is referred to as a…
Q: A biotechnology company offers a direct-to-consumer test called the Carrier Status report that…
A: Genetic testing or DNA testing is done to identify errors or changes occurred in a DNA sequence or…
Q: Imagine that you are in your late 30s or early 40s and decide that you want a child. You realize…
A: “Since you have posted a question with multiple sub-parts, we will solve first three sub-parts for…
Q: underlying a condition for which there is no Genetic testing involves testing individuals for the…
A: GENETIC TESTING : It is a type of tests that identify change in genes that helps us in understanding…
Q: A couple contemplating a pregnancy are in today for an appointment at a genetic counselling clinic…
A: In the healthcare setting the nurse has many roles and responsibilities. These roles include: The…
Q: There are six types of agglutinogen named C,D, E and c,d,e.the first three are dominant and last…
A: In blood typing, antigens on the surfaces of red blood cells (RBCs) are known as agglutinogens.…
Q: A 14-year-old girl has some abnormalities: her height is lower than that of the girls of the same…
A: Chromosomal disorders are caused due to absence or excess or abnormal arrangement of one or more…
Q: Six months pregnant, an expectant mother had a routine ultrasound that showed that the limbs of the…
A: Dwarfism --Most common type of dwarfism is achondroplasia. 97% of achondroplasia cases are caused by…
Q: A. What type of abnormality is shown in Lois' karyotype and explain why she does not have a genetic…
A: Introduction A karyotype is the number and appearance of the complete set of chromosomes in the…
Q: Which of the following methods might have a clue whether child suffering from genetic disease a was…
A: Genetic diseases are the diseases in evict there is either mutation in the DNA itself is if there…
Q: olygenic Inheritance Question: Discuss possible presentation why a given family with 12 children,…
A: Polygenic inheritance Human elements like height, eye variety, and hair tone come in heaps of…
Q: 2a. The pedigree below represents inheritance of rare condition. What pattern of inheritance is most…
A: A pedigree chart is made which indicates the various relationships in a family and with reference to…
Q: (a) What percentage of their children are likely to have a disease phenotype? (b) What percentage…
A: Carrier Genotype A person who carries affected gene but not affected by that disorder because of…
Q: Answer the following questions in two to three sentence! Cerebral Enhancer Jure you in favor of the…
A: The phenotype of an organism or individual is a complex interaction between the genome and the…
Q: Jonah and Jana are siblings. Jonah has the genetic disorder cystic fibrosis, caused by inheriting…
A: INTRODUCTION Cystic fibrosis This is a disorder that cause damages to lung and digestive system.
Q: What is the Chi-squared Goodness of Fit test used to test? a. If the disease is due to…
A: The Chi-square test is used in genetics to find out whether there is a difference in observed and…
Q: b. Two couples are heterozygous for genes that cause albinism, but each gene specifies a different…
A: Disclaimer: Due to multiple sub-parts of the question, the first 3 (b, c, d) are being solved.…
Q: A man with blood type A and a woman of blood type B have a baby girl of blood type O. The man sues…
A: Gene exists in different alternative forms known as allele. Alleles are the genes which on…
Q: Determine which statements could be used as evidence to support the argument that "DNA influences…
A: Cell is the basic unit of life. It consists of proteins, carbohydrates, electrolytes, salts, lipids,…
Q: ow assume that the pedigree shown in question 1 shows the inheritance of a rare genetic disease. a)…
A: Autosomal inheritance of a gene implies that the cistron is found on one in every one of the…
Mrs. Xexy Lucero, GO, 25 years old asks Nurse Zasha about pre symptomatic genetic testing for Huntington's disease. Nurse Zasha should base her response on which of the following? (Select all that apply)
a. One of the parents died of Huntington's disease
b. if the woman is negative for the gene, her children should be tested to see whether or not
they are carriers
c. Presymptomatic testing cannot predict whether or not the gene will be expressed.
d. If the woman is positive for the gene Huntington's, she will develop the disease later in life
e. Both parents are carriers
Trending now
This is a popular solution!
Step by step
Solved in 2 steps
- James sees an online ad for an at-home genetic test that promises to deliver personalized nutritional advice based on an individuals genetic profile. The company can test for genetic variations, the advertisement states, that predispose individuals to developing health conditions such as heart disease and bone loss or that affect how they metabolize certain foods. If such variations are detected, the company can provide specific nutritional advice that will help counteract their effects. Always keen to take any steps available to ensure the best possible health for their family, James and his wife (Sally) decide that they both should be tested, as should their 11-year-old daughter (Patty). They order three kits. Once the kits arrive, the family members use cotton swabs to take cell samples from their cheeks and place the swabs in individually labeled envelopes. They mail the envelopes back to the company, along with completed questionnaires regarding their diets. Four weeks later, they receive three individual reports detailing the test results and providing extensive guidelines about what foods they should eat. Among the results is the finding that James has a particular allele in a gene that may make him vulnerable to the presence of free radicals in his cells. The report suggests that he increase his intake of antioxidants, such as vitamins C and E, and highlights a number of foods that are rich in those vitamins. The tests also show that Sally has several genetic variations that indicate that she may be at risk for elevated bone loss. The report recommends that she try to minimize this possibility by increasing her intake of calcium and vitamin D and lists a number of foods she could emphasize in her diet. Finally, the report shows that Patty has a genetic variation that may mean that she has a lowered ability to metabolize saturated fats, putting her at risk for developing heart disease. The report points to ways in which she can lower her intake of saturated fats and lists various types of foods that would be beneficial for her. A number of companies now offer genetic-testing services, promising to deliver personalized nutritional or other advice based on peoples genetic profiles. Generally, these tests fall into two different categories, with individual companies offering unique combinations of the two. The first type of test detects alleles of known genes that encode proteins that play an established role in, for example, counteracting free radicals in cells or in building up bone. In such cases, it is easy to see why individuals carrying alleles that may encode proteins with lower levels of activity may be more vulnerable to free radicals or more susceptible to bone loss. A second type of test examines genetic variations that may have no clear biological significance (i.e., they may not occur within a gene or may not have a detectable effect on gene activity) but have been shown to have a statistically significant correlation with a disease or a particular physiological condition. For example, a variation may frequently be detected in individuals with heart disease even though the reason for the correlation between the variation and the disease may be entirely mysterious. Do James and Sally have any guarantees that the tests and recommendations are scientifically valid?James sees an online ad for an at-home genetic test that promises to deliver personalized nutritional advice based on an individuals genetic profile. The company can test for genetic variations, the advertisement states, that predispose individuals to developing health conditions such as heart disease and bone loss or that affect how they metabolize certain foods. If such variations are detected, the company can provide specific nutritional advice that will help counteract their effects. Always keen to take any steps available to ensure the best possible health for their family, James and his wife (Sally) decide that they both should be tested, as should their 11-year-old daughter (Patty). They order three kits. Once the kits arrive, the family members use cotton swabs to take cell samples from their cheeks and place the swabs in individually labeled envelopes. They mail the envelopes back to the company, along with completed questionnaires regarding their diets. Four weeks later, they receive three individual reports detailing the test results and providing extensive guidelines about what foods they should eat. Among the results is the finding that James has a particular allele in a gene that may make him vulnerable to the presence of free radicals in his cells. The report suggests that he increase his intake of antioxidants, such as vitamins C and E, and highlights a number of foods that are rich in those vitamins. The tests also show that Sally has several genetic variations that indicate that she may be at risk for elevated bone loss. The report recommends that she try to minimize this possibility by increasing her intake of calcium and vitamin D and lists a number of foods she could emphasize in her diet. Finally, the report shows that Patty has a genetic variation that may mean that she has a lowered ability to metabolize saturated fats, putting her at risk for developing heart disease. The report points to ways in which she can lower her intake of saturated fats and lists various types of foods that would be beneficial for her. A number of companies now offer genetic-testing services, promising to deliver personalized nutritional or other advice based on peoples genetic profiles. Generally, these tests fall into two different categories, with individual companies offering unique combinations of the two. The first type of test detects alleles of known genes that encode proteins that play an established role in, for example, counteracting free radicals in cells or in building up bone. In such cases, it is easy to see why individuals carrying alleles that may encode proteins with lower levels of activity may be more vulnerable to free radicals or more susceptible to bone loss. A second type of test examines genetic variations that may have no clear biological significance (i.e., they may not occur within a gene or may not have a detectable effect on gene activity) but have been shown to have a statistically significant correlation with a disease or a particular physiological condition. For example, a variation may frequently be detected in individuals with heart disease even though the reason for the correlation between the variation and the disease may be entirely mysterious. Do you think that companies should be allowed to market such tests directly to the public, or do you believe that only a physician should be able to order them?James sees an online ad for an at-home genetic test that promises to deliver personalized nutritional advice based on an individuals genetic profile. The company can test for genetic variations, the advertisement states, that predispose individuals to developing health conditions such as heart disease and bone loss or that affect how they metabolize certain foods. If such variations are detected, the company can provide specific nutritional advice that will help counteract their effects. Always keen to take any steps available to ensure the best possible health for their family, James and his wife (Sally) decide that they both should be tested, as should their 11-year-old daughter (Patty). They order three kits. Once the kits arrive, the family members use cotton swabs to take cell samples from their cheeks and place the swabs in individually labeled envelopes. They mail the envelopes back to the company, along with completed questionnaires regarding their diets. Four weeks later, they receive three individual reports detailing the test results and providing extensive guidelines about what foods they should eat. Among the results is the finding that James has a particular allele in a gene that may make him vulnerable to the presence of free radicals in his cells. The report suggests that he increase his intake of antioxidants, such as vitamins C and E, and highlights a number of foods that are rich in those vitamins. The tests also show that Sally has several genetic variations that indicate that she may be at risk for elevated bone loss. The report recommends that she try to minimize this possibility by increasing her intake of calcium and vitamin D and lists a number of foods she could emphasize in her diet. Finally, the report shows that Patty has a genetic variation that may mean that she has a lowered ability to metabolize saturated fats, putting her at risk for developing heart disease. The report points to ways in which she can lower her intake of saturated fats and lists various types of foods that would be beneficial for her. A number of companies now offer genetic-testing services, promising to deliver personalized nutritional or other advice based on peoples genetic profiles. Generally, these tests fall into two different categories, with individual companies offering unique combinations of the two. The first type of test detects alleles of known genes that encode proteins that play an established role in, for example, counteracting free radicals in cells or in building up bone. In such cases, it is easy to see why individuals carrying alleles that may encode proteins with lower levels of activity may be more vulnerable to free radicals or more susceptible to bone loss. A second type of test examines genetic variations that may have no clear biological significance (i.e., they may not occur within a gene or may not have a detectable effect on gene activity) but have been shown to have a statistically significant correlation with a disease or a particular physiological condition. For example, a variation may frequently be detected in individuals with heart disease even though the reason for the correlation between the variation and the disease may be entirely mysterious. Do you think parents should be able to order such a test for their children? What if the test indicates that a child is at risk for a disease for which there is no known cure?
- James sees an online ad for an at-home genetic test that promises to deliver personalized nutritional advice based on an individuals genetic profile. The company can test for genetic variations, the advertisement states, that predispose individuals to developing health conditions such as heart disease and bone loss or that affect how they metabolize certain foods. If such variations are detected, the company can provide specific nutritional advice that will help counteract their effects. Always keen to take any steps available to ensure the best possible health for their family, James and his wife (Sally) decide that they both should be tested, as should their 11-year-old daughter (Patty). They order three kits. Once the kits arrive, the family members use cotton swabs to take cell samples from their cheeks and place the swabs in individually labeled envelopes. They mail the envelopes back to the company, along with completed questionnaires regarding their diets. Four weeks later, they receive three individual reports detailing the test results and providing extensive guidelines about what foods they should eat. Among the results is the finding that James has a particular allele in a gene that may make him vulnerable to the presence of free radicals in his cells. The report suggests that he increase his intake of antioxidants, such as vitamins C and E, and highlights a number of foods that are rich in those vitamins. The tests also show that Sally has several genetic variations that indicate that she may be at risk for elevated bone loss. The report recommends that she try to minimize this possibility by increasing her intake of calcium and vitamin D and lists a number of foods she could emphasize in her diet. Finally, the report shows that Patty has a genetic variation that may mean that she has a lowered ability to metabolize saturated fats, putting her at risk for developing heart disease. The report points to ways in which she can lower her intake of saturated fats and lists various types of foods that would be beneficial for her. A number of companies now offer genetic-testing services, promising to deliver personalized nutritional or other advice based on peoples genetic profiles. Generally, these tests fall into two different categories, with individual companies offering unique combinations of the two. The first type of test detects alleles of known genes that encode proteins that play an established role in, for example, counteracting free radicals in cells or in building up bone. In such cases, it is easy to see why individuals carrying alleles that may encode proteins with lower levels of activity may be more vulnerable to free radicals or more susceptible to bone loss. A second type of test examines genetic variations that may have no clear biological significance (i.e., they may not occur within a gene or may not have a detectable effect on gene activity) but have been shown to have a statistically significant correlation with a disease or a particular physiological condition. For example, a variation may frequently be detected in individuals with heart disease even though the reason for the correlation between the variation and the disease may be entirely mysterious. What kinds of regulations, if any, should be in place to ensure that the results of these tests are not abused?The world can be a scary place. There are many disease causing organisms and genetic disorders that can make life difficult. As you read the chapter, be thinking about your family history of genetic disorders, how these disorders are passed on through generations, and what types of testing can be done to look for these alleles. In this exercise you will reflect on the pros and cons of genetic testing and how it may affect you. Please remember to add a question to engage your classmates in the discussion. What might the consequences be of having this information (e.g. health insurance coverage, privacy, etc.)?Imagine that you are in your late 30s or early 40s and decide that you want a child. You realize that you’re at greater risk of having a child with Down’s Syndrome. What sorts of genetic screening are available today? If you find out that this child has this condition, do you think it’s appropriate to have an abortion? Why or why not? Question: Does elective abortion of fetuses with physical or other developmental disabilities have an effect on the perception of personhood, dignity, and rights in society? Explain.
- Jonah and Jana are siblings. Jonah has the genetic disorder cystic fibrosis, caused by inheriting one copy from each parent of a mutation in the CF gene. Jana does not have cystic fibrosis. Which of the following statements is/are true? (Select all that are true) a)Jana does not have the gene that when mutant causes cystic fibrosis. b)Jana has the gene that when mutant causes cystic fibrosis. c)Jana has two copies of the allele that causes cystic fibrosis. d)Jana does not have two copies of the allele that causes cystic fibrosis.Which of the examples of genetic testing below are prognostic tests? Which are diagnostic? (a) Individual sequencing (personal genomics) identifies a mutation associated with Alzheimer’s disease. (b) ASO testing determines that an individual is a carrier for the mutant b@globin allele (bS) found in sickle-cell anemia. (c) DNA sequencing of a breast tumor reveals mutations in the BRCA1 gene. (d) Genetic testing in a healthy teenager identifies an SNP correlated with autism. (e) An adult diagnosed with Asperger syndrome (AS) has a genetic test that reveals a SNP in the GABRB3 gene that is significantly more common in people with AS than the general population.A 20-year-old woman comes to your genetic counselling center because she knows that Huntington disease occurs in members of her family. Huntington is an autosomal dominant disease that often becomes apparent around 35–40 years of age. Her paternal grandfather was afflicted, but so far her 41 year old father shows no symptoms. Her two great-great grandmothers on her father's side were healthy well into their 90s, and one of her great-great grandfathers died of unknown causes at 45. Testing for Huntington disease is extremely expensive, but she is concerned that she may fall victim to this disease and wants to plan her life accordingly. After examining her pedigree you advise her to: not get tested because her father is only a carrier and it is very unlikely her mother is a carrier. not get tested because there is no possibility that she is homozygous. get tested because her father could be a carrier. not get tested because only males in her family get the disease. not get tested…
- Many genetic counselors will not provide presymptomatic genetic testing for Huntington disease to people below the age of 18. Why are there concerns about offering this and many other genetic tests to minors? What types of presymptomatic genetic testing might be appropriate for minors?Mike was referred for genetic counseling because he was concerned about his extensive family history of colon cancer. That family history was highly suggestive of hereditary nonpolyposis colon cancer (HNPCC). This predisposition is inherited as an autosomal dominant trait, and those who carry the mutant allele have a 75% chance of developing colon cancer by age 65. Mike was counseled about the inheritance of this condition, the associated cancers, and the possibility of genetic testing (on an affected family member). Mikes aunt elected to be tested for one of the genes that may be altered in this condition and discovered that she did have an altered MSH2 gene. Other family members are in the process of being tested for this mutation. Once a family member is tested for the mutant allele, is it hard for other family members to remain unaware of their own fate, even if they did not want this information? How could family dynamics help or hurt this situation?Mike was referred for genetic counseling because he was concerned about his extensive family history of colon cancer. That family history was highly suggestive of hereditary nonpolyposis colon cancer (HNPCC). This predisposition is inherited as an autosomal dominant trait, and those who carry the mutant allele have a 75% chance of developing colon cancer by age 65. Mike was counseled about the inheritance of this condition, the associated cancers, and the possibility of genetic testing (on an affected family member). Mikes aunt elected to be tested for one of the genes that may be altered in this condition and discovered that she did have an altered MSH2 gene. Other family members are in the process of being tested for this mutation. Is colon cancer treatable? What are the common treatments, and how effective are they?