Translate the original sequence (for these short sequences start translation at the first nucleotide) Second letterAGUUU Phenyl-UUC alanineUCUUCCUCAUCGUAUUACUGUUGC CysteineTyrosineSerineUAA Stop codonUAG Stop codon UGG TryptophanUUAUUGUGA Stop codonALeucineGCAUCACCUUCUCCỦACUGCGUCCCGA ArginineCGGCCUCHistidineLeucineProlineCCACGCAACAG GlutamineAUUAUC IsoleucineA AUAAGUAGC SerineAAUACUACCАCAMethionine: ACGAAC AsparagineThreonineAAAAAG LysineAGAAUGstart codonAGG ArginineGUUGUCGGUAGCUGOCGAU AsparticGAC acidGGUGGCValineAlanineGlycineGCAGAAGlutamicGAG acidGGAGGGAGUGGCGGТуре ofEffect:protein/amino acidOriginalAltered sequencemutation:sequenceDNAnucleotideMRNAAUUCGAGUAAUUCGGGUAaminoacidMRNAACGGAACCGACGGUACCGaminoacidMRNAGCUAGAAGUGCUUGAAGUaminoacidGGCGCUACAUCA GGCAGCUACAUCAMRNAaminoacidMRNAGGCGCUACAUCAGGGCUACAUCAaminoacidFirst letterThird letter For each of the five short mRNA nucleotide sequences given in the table below:3. Translate the original sequence (for these short sequences start translation atthe first nucleotide)4. Identify (and highlight or underline) the one nucleotide difference betweenthe original (left) and altered (right) sequences5. For each altered nucleotide sequence give the type of mutation (effect at theDNA/nucleotide level; see #1 above)6. Translate each changed sequence. Does the mutation result in a change in theamino acid sequence? If so, what is the effect of the mutation on proteinstructure (amino acid sequence; see #2 above)

A mutation is a sudden, stable and inheritable alteration in the base sequence of a gene which is…

Answered: Original sequence Altered sequence…

Original sequence Altered sequence protein/ amino acid mutation: DNA nucleotide AUUCGAGUA AUUCGGGUA MRNA amino acid ACGGAACCG ACGGUACCG MRNA amino acid MRNA GCUAGAAGU GCUUGAAGU amino acid

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter9: Gene Expression And Gene Regulation

Section: Chapter Questions

Problem 16QP: Given the following tRNA anticodon sequence, derive the mRNA and the DNA template strand. Also,...

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Question

Translate the original sequence (for these short sequences start translation at the first nucleotide)

Second letter
A
G
UUU Phenyl-
UUC alanine
UCU
UCC
UCA
UCG
UAU
UAC
UGU
UGC Cysteine
Tyrosine
Serine
UAA Stop codon
UAG Stop codon UGG Tryptophan
UUA
UUG
UGA Stop codon
A
Leucine
G
CAU
CAC
CUU
CUC
CỦA
CUG
CGU
CC
CGA Arginine
CGG
CCU
C
Histidine
Leucine
Proline
CCA
CG
CAA
CAG Glutamine
AUU
AUC Isoleucine
A AUA
AGU
AGC Serine
AAU
ACU
ACC
АCA
Methionine: ACG
AAC Asparagine
Threonine
AAA
AAG Lysine
AGA
AUG
start codon
AGG Arginine
GUU
GUC
G
GUA
GCU
GOC
GAU Aspartic
GAC acid
GGU
GGC
Valine
Alanine
Glycine
GCA
GAA
Glutamic
GAG acid
GGA
GGG
A
GUG
GCG
G
Туре of
Effect:
protein/
amino acid
Original
Altered sequence
mutation:
sequence
DNA
nucleotide
MRNA
AUUCGAGUA
AUUCGGGUA
amino
acid
MRNA
ACGGAACCG
ACGGUACCG
amino
acid
MRNA
GCUAGAAGU
GCUUGAAGU
amino
acid
GGCGCUACAUCA GGCAGCUACAUCA
MRNA
amino
acid
MRNA
GGCGCUACAUCA
GGGCUACAUCA
amino
acid
First letter
Third letter

For each of the five short mRNA nucleotide sequences given in the table below:
3. Translate the original sequence (for these short sequences start translation at
the first nucleotide)
4. Identify (and highlight or underline) the one nucleotide difference between
the original (left) and altered (right) sequences
5. For each altered nucleotide sequence give the type of mutation (effect at the
DNA/nucleotide level; see #1 above)
6. Translate each changed sequence. Does the mutation result in a change in the
amino acid sequence? If so, what is the effect of the mutation on protein
structure (amino acid sequence; see #2 above)

Definition Definition A complex molecule that makes up a fundamental unit of a DNA or RNA molecule. Nucleotides are composed of a sugar, a nitrogenous base, and a phosphoric acid.

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