Pyruvate dehydrogenase deficiency is a fatal disease usually diagnosed in children. Symptoms include severe neurological damage. Elevated blood levels of lactate, pyruvate, and alanine are also seen. Explain how the deficiency of pyruvate dehydrogenase causes these elevated values.

Q: Briefly describe the dual role of lipoic acid in the pyruvate dehydrogenase complex

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Q: In the human body, under oxygen rich and oxygen poor conditions, respectively, pyruvate is converted…

A: Pyruvate has different fates under oxygen-rich and oxygen-poor conditions.

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Q: Explain why the reaction catalyzed by the pyruvate dehydrogenase complex is a crucial juncture in…

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Q: Which of the following enzyme catalyzes the conversion of pyruvate to lactate? O a) Pyruvate…

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Q: Which of the following cofactors is NOT used by the pyruvate dehydrogenase complex? a. NAD+ b. FAD…

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Q: Give one metabolic intermediate that is released as pyruvate is oxidized by the pyruvate…

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Q: Which of these statements about lactate dehydrogenase is true? a.It is a protein. b.It oxidizes…

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Q: NADH can act as an inhibitor of isocitrate dehydrogenase and a-ketoglutarate dehydrogenase. This is…

A: Hi! As you have posted multiple questions  which is to be answered, we are authored to answer  first…

Q: Is the statement true or false?

A: Glycolysis is the process of breakdown of glucose to obtain energy by the cells for fulfilling their…

Q: Pyruvate is converted to acetyl-CoA by the enzymes of the _____________ enzyme complex.

A: Pyruvate is produced in the cytoplasm by glycolysis.

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Q: Glycerol generated from TG hydrolysis in adipocytes is converted by the liver into _____________,…

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Q: Why is pyruvate referred to as the hub of glucose oxidation?

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Q: During glycolysis, glucose is converted to pyruvate. Pyruvate then is converted to Acetyl coA and…

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Q: Which of the following enzymes are inhibited by ATP? (choose all the correct answers) citrate…

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Q: Pyruvate has three different fates. What are the three different molecules pyruvate is converted…

A: Pyruvate is majorly released from the process of glycolysis, which is a three-carbon compound.

Q: Fourteen NADPH molecules are required to produce one molecules of palmitic acid from acetyl CoA.…

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Q: High amount of citrate decreases the activity of fructose 1,6-bisphosphatase. True or False

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Q: CH3CH2OH + NAD+ --> CH3CHO + NADH +H+ Explain how this reaction inhibits the production of pyruvate…

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Q: Oxidation of pyruvate is completed in the Cytoplasm of mitochondrion with the presence of

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Q: How does pyruvate from glycolysis get to the pyruvate dehydrogenase complex?

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Q: Fatty acid degradation stimulates the citric acid cycle through the activation of pyruvate…

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Q: Which glycolysis reactions are catalyzed by the following enzymes?(a) Pyruvate kinase(b)…

A: Glycolysis is the process, during which glucose molecule is converted into molecules of pyruvate.

Q: Describe the role played by each enzyme, cofactor, andcoenzyme of the pyruvate dehydrogenase complex

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Q: explain the difference between pyruvate carrier and pyruvate dehydrogenase complex?

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Q: Does Pyruvate Dehydrogenase Complex have coenzymes and Allosteric regulation?

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Q: What are the five enzymes (including regulatory enzymes) that constitute the pyruvate dehydrogenase…

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Q: The heart cannot convert lactate back to glucose, as the liver does, but instead uses it as a fuel.…

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Q: Is the statement much of the regulation of gluconeogenesis a result of the inhibition of glycolysis…

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