Sickle Cell Anemia Sickle cell anemia is a group of blood disorders that develop when a person inherits a specific recessive gene mutation. Gene mutations are permanent changes in a genetic sequence. The sickle cell mutation affects the structure of hemoglobin: hemoglobin allows red blood cells to carry oxygen. In order for a person to have sickle cell anemia, they have to inherit two copies of the recessive allele, one from each parent. The diagram shows the genotypes of an unaffected person and a person with sickle cell anemia Explain how inheriting the sickle cell mutation affects the cellular processes of transcription and translation.

Sickle Cell Anemia Sickle cell anemia is a group of blood disorders that develop when a person inherits a specific recessive gene mutation. Gene mutations are permanent changes in a genetic sequence. The sickle cell mutation affects the structure of hemoglobin: hemoglobin allows red blood cells to carry oxygen. In order for a person to have sickle cell anemia, they have to inherit two copies of the recessive allele, one from each parent. The diagram shows the genotypes of an unaffected person and a person with sickle cell anemia Explain how inheriting the sickle cell mutation affects the cellular processes of transcription and translation.

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter19: Introduction To Genetics

Section: Chapter Questions

Problem 9CT

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Sickle cell anemia is a disease that is caused by a mutation in the gene that produces hemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces hemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell anemia and are described as having the sickle cell trait. Individuals that are homozygous for the sickle allele (HbSHbS) only produce "sickle" hemoglobin and develop sickle cell disease.A man who is homozygous for the normal allele married a woman with the sickle cell trait. What is the expected probability of this couple having a boy with the sickle cell trait? Record your answer as a value between 0 and 1 rounded to two decimal places.Answer
Sickle cell anemia is a disease that is caused by a mutation in the gene that produces hemoglobin. Hemoglobin carries oxygen in red blood cells. The HbA allele produces normal hemoglobin and the HbS allele produces hemoglobin that sticks together and causes red blood cells to sickle. Heterozygous individuals (HbAHbS) produce both normal and "sickle" hemoglobin so the HbA and HbS alleles are codominant. Heterozygotes do not develop sickle cell anemia and are described as having the sickle cell trait. Individuals that are homozygous for the sickle allele (HbSHbS) only produce "sickle" hemoglobin and develop sickle cell disease. A man with the sickle cell trait married a woman with the sickle cell trait. Determine the probability that they will have children with the sickle cell trait or sickle cell disease.Record your answer as a value between 0 and 1 rounded to two decimal places. Answer
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