Some enzymes can catalyze a reaction involving NADH but cannot catalyze a reaction that uses NADPH. Why may this be?

Human Physiology: From Cells to Systems (MindTap Course List)
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ISBN:9781285866932
Author:Lauralee Sherwood
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Chapter2: Cell Physiology
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Problem 10RE: Using the answer code on the right, indicate which form of energy production is being described: 1....
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Some enzymes can catalyze a reaction involving NADH but cannot catalyze a reaction that uses NADPH. Why may this be?

When the substrate concentration is below the Km for an enzyme, what “order” will best explain the
reaction? Explain.

The cells that line the intestine have a transporter called GLUT5. While it can transport both fructose and glucose but has a much lower Km for fructose. Describe a physiological situation where the GLUT5 transporter is transporting fructose and glucose at the same rate. [consider using a graph to support your answer] 

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