Synthesis of amides from acid chlorides is an effective tool for creating many different compounds. One such compound is DEET, a.k.a. (N,N)-Diethyl-m-toluamide, a powerful insect repellent. Propose a chemical synthesis of DEET from m-toluic acid and any other necessary reagents. Provide a literature reference for any reaction that is not common knowledge.

Synthesis of amides from acid chlorides is an effective tool for creating many different compounds. One such compound is DEET, a.k.a. (N,N)-Diethyl-m-toluamide, a powerful insect repellent. Propose a chemical synthesis of DEET from m-toluic acid and any other necessary reagents. Provide a literature reference for any reaction that is not common knowledge.

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter18: Functional Derivatives Of Carboxylic Acids

Section: Chapter Questions

Problem 18.42P

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