The chemical reaction to make acetylsalicylic acid (aspirin) is shown below. C7H6O3 + C4H6O3 ----> C9H8O4 + C2H4O2 salicylic acid + acetic anhydride ----> acetylsalicylic acid + acetic acid Answer the following questions regarding this reaction. a. If you weighted 3.65 g of salicylic acid, how many grams of aspirin would be created? Use correct number of significant figures, do not write units, write numbers only. b. If the average percent yield of this type of reaction is 95%. How many milligrams of salicylic acid do you need to weight to make 325 mg (an adult dose) of aspirin tablet? Use correct number of significant figures, do not write units, write numbers only.

The chemical reaction to make acetylsalicylic acid (aspirin) is shown below. C7H6O3 + C4H6O3 ----> C9H8O4 + C2H4O2 salicylic acid + acetic anhydride ----> acetylsalicylic acid + acetic acid Answer the following questions regarding this reaction. a. If you weighted 3.65 g of salicylic acid, how many grams of aspirin would be created? Use correct number of significant figures, do not write units, write numbers only. b. If the average percent yield of this type of reaction is 95%. How many milligrams of salicylic acid do you need to weight to make 325 mg (an adult dose) of aspirin tablet? Use correct number of significant figures, do not write units, write numbers only.

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter9: Addition Via Cyclic Intermediate

Section: Chapter Questions

Problem 2E

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you plan to carry out the syn- thesis of aspirin (acetylsalicylic acid) by reacting salicylic acid with acetic anhydride, using 85% phosphoric acid as a catalyst. In addition to aspirin, acetic acid will be a side product. Using one of the suggested online sources (such as the Sigma-Aldrich or Acros Organics websites), look up the molar masses for all of the reagents and products in this reaction. Also look up the melting points of salicylic acid and acetylsalicylic acid and the boiling points and densities of acetic anhydride and acetic acid. Your answers should include both the molar masses and the physical properties for all four reagents and products.
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