The compound 4-isobutylacetophenone is needed for the synthesis of ibupro- fen. Propose a synthesis of 4-isobutylacetophenone from benzene and any other necessary reagents. several steps COOH 4-Isobutylacetophenone Ibuprofen (racemic)
Q: Treating trimethylamine with 2-chloroethyl acetate gives acetylcholine as its chloride.…
A: Trimethylamine reacts with 2-chloroethylacetate by SN2 mechanism. Thus the bond breaking and bond…
Q: Starting with 3-nitroaniline, show how to prepare the following compounds. Q.) 1,3-Dihydroxybenzene…
A: 3-nitroaniline is converted to a diamine by undergoing hydrogenation in presence of nickel. Diamine…
Q: An α, β-unsaturated carbonyl compound can be prepared by a reaction known as a…
A: The given reaction is represented as follows:
Q: Draw a structural formula for the product of the reaction of acetophenone with reagent Q. N2H4, KOH…
A: Given reaction:
Q: Propose a mechanism for formation of 2-carbethoxy-4-butanolactone and 4-butanolactone…
A: 2-carbethoxy-4-butanolactone
Q: Show how (A) can be converted to tolciclate. Use 3-methyl-N-methylaniline
A:
Q: Addition of one mole of HCl to isoprene gives 4-chloro-2-methyl-2-butene as the major product.…
A: The reaction between isoprene and HCl is an addition reaction. The mechanism has been discussed…
Q: trans-stilbene trans-stilbene 2-bromo-1,2-diphenylethanol (a bromohydrin) Br 24 OH B. NBS C.DMSO…
A: A question based on introduction to organic chemistry that is to be accomplished.
Q: 2-Phenylindole is prepared from the reaction of acetophenone and phenylhydrazine, a method known as…
A: The Mechanism for Fischer Indole Synthesis : Explanation : The synthesis of Fischer…
Q: 3. Provide a retrosynthetic analysis of the following compound from cyclohexene and any other…
A:
Q: Ga 14 Epoxides Draw structures and names for the synthetic outcomes when 2,2-dimethyloxirane (AKA…
A: Under basic condition, nucleophile attacks on less hindered side of epoxide Under acidic condition,…
Q: Devise a synthesis of each of the following compounds. Besidesinorganic reagents, you may use…
A: In the given synthesis, new C-C bonds are formed using Grignard reagent and Wittig reaction.
Q: Amobarbital is a sedative marketed under the trade name Amytal. Propose a synthesis of amobarbital,…
A: Structure of Amobarbital is,
Q: 2,6-Dimethoxybenzoic acid was needed for a synthesis of the β-lactam antibiotic methicillin. Show…
A: The synthesis of 2,6-dimethoxybenzoic acid from 2-bromo-1,3-benzenediol has to be given.
Q: methamphetamine dopamine 14 Synthesize Novocaine from benzene and any other reagents of four carbons…
A: Following is the conversion of Benzene to Novocaine.
Q: [ 20] Which sequence of reactions would yield following compound (benzophenone) as product ? ( a)…
A: The answer will be D. Please find below the reaction mechanism.
Q: Fischer esterification cannot be used to prepare tert-butyl esters. Instead, carboxylic acids are…
A: From question we have:
Q: 3-Amino-2-oxindole catalyzes the decarboxylation of a-keto acids.a. Propose a mechanism for the…
A: The decarboxylation of α-keto acids takes place in presence of 3-amino-2-oxindole. When 3-amino-2-…
Q: Propose a mechanism for this reaction
A:
Q: Show how m-toluidine can be converted tom-toluidineCH3 NH2the following compounds, using any…
A:
Q: Thiols can be prepared from the reaction of thiourea with an alkyl halide, followed by…
A: (a) The given reaction is,
Q: The following compound used in perfumery has a violet-like scent. Propose a synthesis of this…
A: Organic synthesis is a special branch of chemical synthesis which concerns the systematic…
Q: Identify the reactions needed to prepare A) (1) Acetyl chloride, (2) LIAIH4, (3) Benzyl bromide B)…
A: N-benzyl-N-methylbutylamine from 1-aminobutane can be synthesized by using = B) (1)…
Q: Show how m-toluidine can be converted tom-toluidineCH3 NH2the following compounds, using any…
A: a.
Q: The leukotrienes, important components in the asthmatic response, are synthesized from arachidonic…
A: The conversion of arachidonic acid to 5-HPETE is three steps. The initial step includes the…
Q: The reaction of cyclohexanone (1) and N,N-dimethylamine (2) with (i) sodium triacetoxyborohydride…
A: This is an example of reductive amination reaction in which an aldehyde or ketone reacts with amine…
Q: Show how to synthesize the following compounds, using appropriate carboxylic acids and…
A:
Q: The following scheme shows the retrosynthetic analysis of 1-isopentylaziridine to form series of…
A:
Q: „NH2 .COOH Aniline Benzoic acid Benzoic acid can be prepared from aniline via aryl diazonium ion.…
A: Given : We have to tell how the following conversion will take place.
Q: Select the reagents you would use to synthesize the compound below from benzene. (More than one step…
A:
Q: yニ,ニ N P 'CI HO, Q んこんこんn S R to `Br
A:
Q: Thiols can be prepared from the reaction of thiourea with an alkyl halide, followed by…
A: (a) The given reaction is,
Q: Butacetin is an analgesic (pain-killing) agent that is synthesized com- mercially from…
A: The structure of p-Fluoronitrobenzene is; Butacetin is synthesized from p-Fluoronitrobenzene.
Q: Predict the products from reaction of 2-heptyne with following reagents: (a) 2 equiv Br2. (b) H20,…
A:
Q: 10.₁ amide? A. one equivalent B. two equivalents C. this conversion is not possible D. one…
A: Following questions are belongs to the reaction mechanism.
Q: Starting with 3-nitroaniline, show how to prepare the following compounds. Q.) 3-Bromoaniline
A: 3-Nitroaniline is converted to arenediazonium salt by reacting with NaNO2 in presence of aqueous…
Q: 4. Terpenes are substances derived from active isoprene or isopropyl pyrophosphate, they are the…
A:
Q: Novocaine is a local anesthetic most commonly used in dental procedures to numb the area around a…
A: When Benzene reacts with MeCl/anh. AlCl3 (Friedel-Craft alkylation) then toluene is formed which on…
Q: Show the product of treating y-butyrolactone with reagent.
A: The product of gamma-butyrolactone with the given reagent should be shown.
Q: Propose a synthesis, showing reagents and conditions, to make 4-bromoaniline starting from benzene.…
A: First we need to convert the bromine into aniline to produce 4-bromoaniline finally. Hence to do…
Q: 二 ニ。 二 二人 HO, んこんー ん HO.
A: N. Amide to amine using LiAlH4. O. Acid chloride reaction with amine (Acyl substitution). P. Acid is…
Q: Identify the compound (Z) formed when aniline is subjected to the following series of reactions:…
A:
Q: 3-Amino-2-oxindole catalyzes the decarboxylation of a-keto acids. a. Propose a mechanism for the…
A: The decarboxylation of α-keto acids takes place in presence of 3-amino-2-oxindole. When 3-amino-2-…
Q: Following are two possible retrosynthetic analyses for the anticholinergic drug cycri- mine. Fill in…
A: Reaction of Piperidine with epoxide ring initiates the ring opening of epoxide and the product on…
Q: NH CH3 N-benzylacetamide
A:
Q: Following is a retrosynthetic analysis for the synthesis of the herbicide (S)-Metolachlor from…
A: The retrosynthetic method is used to predict the starting material from product structure by…
Q: Benzamide, CoHsCONH2 1. is an amino acid 2. can be converted to phenylamine (aniline) on warming…
A: The given compound is Benzamide. The structure of the Benzamide is as follows:
Q: propose a synthesis of meso-4,5-dibromooctane
A: The given compound (meso-4,5-dibromooctane) can be synthesisedfrom oct-4-yne. Meso compounds have…
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 2 images
- One step in the urea cycle for ridding the body of ammonia is the conversion of argininosuccinate to the amino acid arginine plus fumarate. Propose a mechanism for the reaction, and show the structure of arginine.The polyurethane foam used for home insulation uses methane-diphenyldiisocyanate (MDI) as monomer. The MDI is prepared by acid-catalyzed reaction of aniline with formaldehyde, followed by treatment with phosgene, COCl2. Propose mechanisms for both steps.Show how to synthesize the following compounds, using appropriate carboxylic acids and amines.ON(CH2CH3)2N,N-diethyl-meta-toluamide(DEET insect repellent)CH3 C(a)NH CacetanilideOCH3(b)CON(CH3) H 2N,N-dimethylformamide (DMF)
- Devise a synthesis of each of the following compounds. Besidesinorganic reagents, you may use hydrocarbons and halides having ≤ 6C′s, and CH2=CHCOOCH3 as starting materials. Each synthesis must use at least one of the carbon–carbon bond-forming reactions.The following scheme shows the retrosynthetic analysis of 1-isopentylaziridine to form series of intermediates via Functional Group Inversion (FGI). Choose the correct reagents of N-S for the respective conversionA step in a synthesis of PGE1 (prostaglandin E1, alprostadil) is the reaction of a trisubstituted cyclohexene with bromine to form a bromolactone. Propose a mechanism for formation of this bromolactone and account for the observed stereochemistry of each substituent on the cyclohexane ring. Alprostadil is used as a temporary therapy for infants born with congenital heart defects that restrict pulmonary blood flow. It brings about dilation of the ductus arteriosus, which in turn increases blood flow in the lungs and blood oxygenation.
- Show how the synthetic scheme developed in Problem 23.67 can be modified to synthesize this triiodobenzoic acid X-ray contrast agent.Following is a synthesis for toremifene, a nonsteroidal estrogen antagonist whose structure is closely related to that of tamoxifen. (a) This synthesis makes use of two blocking groups, the benzyl (Bn) group and the tetrahydropyranyl (THP) group. Draw a structural formula of each group and describe the experimental conditions under which it is attached and removed. (b) Discuss the chemical logic behind the use of each blocking group in this synthesis. (c) Propose a mechanism for the conversion of D to E. (d) Propose a mechanism for the conversion of F to toremifene. (e) Is toremifene chiral? If so, which of the possible stereoisomers are formed in this synthesis?Amino acids can be prepared by reaction of alkyl halides with diethyl acetamidomalonate, followed by heating the initial alkylation product with aqueous HCl. Show how you would prepare alanine, CH3CH(NH2)CO2H, one of the twenty amino acids found in proteins, and propose a mechanism for acid-catalyzed conversion of the initial alkylation product to the amino acid.
- Propose a synthesis of diethylstilbestrol (Problem 27-44) from phenol and any other organic compound required.Following is a retrosynthetic analysis for an intermediate in the industrial synthesis of vitamin A. (a) Addition of one mole of HCl to isoprene gives 4-chloro-2-methyl-2-butene as the major product. Propose a mechanism for this addition and account for its regioselectivity. (b) Propose a synthesis of the vitamin A precursor from this allylic chloride and ethyl acetoacetate.Dihydropyran is synthesized by treating tetrahydrofurfuryl alcohol with an arenesulfonic acid, ArSO3H. Propose a mechanism for this conversion.