The eukaryotic chromosomes are linear DNA molecules with free 3'-OH and 5'-PO3- ends. DNA free ends are signals of double strand breaks, which are highly detrimental for the cell. Using the diagram below as a reference, describe structurally how telomeres resolve this problem. Make sure to highlight the interactions involved, the nature of the telomeric sequences and the correct nomenclature for the structure formed. 5' Telomeric DNA TTGGGGTTGGGGTTGGGG 3' TGGGGז AACCCC AACCCCAACCCC AACCCCAACCCC Non-telomeric DNA TTGGGG 3' TGGזGG AACCCC. 5' AACCCC AACCCC TTGGGG TTGGGG TTGGGGTTGGGGTTGGGG AACCCCAACCCCAAC C AACCCC TGGGGז
The eukaryotic chromosomes are linear DNA molecules with free 3'-OH and 5'-PO3- ends. DNA free ends are signals of double strand breaks, which are highly detrimental for the cell. Using the diagram below as a reference, describe structurally how telomeres resolve this problem. Make sure to highlight the interactions involved, the nature of the telomeric sequences and the correct nomenclature for the structure formed. 5' Telomeric DNA TTGGGGTTGGGGTTGGGG 3' TGGGGז AACCCC AACCCCAACCCC AACCCCAACCCC Non-telomeric DNA TTGGGG 3' TGGזGG AACCCC. 5' AACCCC AACCCC TTGGGG TTGGGG TTGGGGTTGGGGTTGGGG AACCCCAACCCCAAC C AACCCC TGGGGז
Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter14: Gene Regulation
Section: Chapter Questions
Problem 8TYU: Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription...
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