The following figure depicts the breakdown of purine nucleotides, which are the nucleotides with adenine and guanine bases found in DNA and RNA. Note that uric acid is the final product of this pathway in humans. Dr. Miloslavsky and the patient discussed her history of treatment with three different drugs. You will learn more about these specific drugs as we proceed with this case. These drugs all act in some way to affect the breakdown of purines. Which of the following would reasonably be effective therapies for treating gout? (select all that apply) A drug that increases the concentration of purines entering this pathway. A drug that catalyzes the breakdown of uric acid into another compound. A drug that blocks the enzyme that catalyzes the formation of uric acid. A drug that catalyzes the breakdown of guanosine into guanine
Enzyme kinetics
In biochemistry, enzymes are proteins that act as biological catalysts. Catalysis is the addition of a catalyst to a chemical reaction to speed up the pace of the reaction. Catalysis can be categorized as either homogeneous or heterogeneous, depending on whether the catalysts are distributed in the same phase as that of the reactants. Enzymes are an essential part of the cell because, without them, many organic processes would slow down and thus will affect the processes that are important for cell survival and sustenance.
Regulation of Enzymes
A substance that acts as a catalyst to regulate the reaction rate in the living organism's metabolic pathways without itself getting altered is an enzyme. Most of the biological reactions and metabolic pathways in the living systems are carried out by enzymes. They are specific for their works and work in particular conditions. It maintains the best possible rate of reaction in the most stable state. The enzymes have distinct properties as they can proceed with the reaction in any direction, their particular binding sites, pH specificity, temperature specificity required in very few amounts.
The following figure depicts the breakdown of purine
Dr. Miloslavsky and the patient discussed her history of treatment with three different drugs. You will learn more about these specific drugs as we proceed with this case. These drugs all act in some way to affect the breakdown of purines. Which of the following would reasonably be effective therapies for treating gout? (select all that apply)
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