The following pedigree represent a disease that is rery rare in the human population and completely penetrant What is the mode of inheritance? What is the probability that a child indicated with an "A"will inherit the disease? SHOWYOUR WORK A?
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- As it turned out, one of the tallest Potsdam Guards had an unquenchable attraction to short women. During his tenure as guard, he had numerous clandestine affairs. In each case, children resulted. Subsequently, some of the childrenwho had no way of knowing that they were relatedmarried and had children of their own. Assume that two pairs of genes determine height. The genotype of the 7-foot-tall Potsdam Guard was A9A9B9B9, and the genotype of all of his 5-foot clandestine lovers was AABB. An A9 or B9 allele in the offspring each adds 6 inches to the base height of 5 feet conferred by the AABB genotype. a. What were the genotypes and phenotypes of all the F1 children? b. Diagram the cross between the F1 offspring, and give all possible genotypes and phenotypes of the F2 progenyAn organism of the genotype AaBbCc was testcrossed to a triplyrecessive organism (aabbcc). The genotypes of the progeny are inthe following table.AaBbCc 20 AaBbcc 20aabbCc 20 aabbcc 20AabbCc 5 Aabbcc 5aaBbCc 5 aaBbcc 5 a.) Assuming simple dominance and recessiveness in each genepair, if these three genes were all assorting independently,how many genotypic and phenotypic classes would result inthe offspring, and in what proportion? b.) Answer part (a) again, assuming the three genes are sotightly linked on a single chromosome that no crossovergametes were recovered in the sample of offspring. c.) What can you conclude from the actual data about thelocation of the three genes in relation to one another?In letter B: If the map distance equals the number of recombinant/total of offspring, wouldn't it be 24/806 x 100? Wouldn't we add both recombinants? Can you explain letter C? I don't grasp that concept well. And since I'm using my question already, would you be able to answer D. Thank you!
- An organism of the genotype AaBbCc was testcrossed to a triply recessive organism (aabbcc). The genotypes of the progeny are presented in the following table. 20 AaBbCc 20 AaBbcc 20 aabbCc 20 aabbcc 5 AabbCc 5 Aabbcc 5 aaBbCc 5 aaBbcc (a) If these three genes were all assorting independently, how many genotypic and phenotypic classes would result in the offspring, and in what proportion, assuming simple dominance and recessiveness in each gene pair? (b) Answer part (a) again, assuming the three genes are so tightly linked on a single chromosome that no crossover gametes were recovered in the sample of offspring. (c) What can you conclude from the actual data about the location of the three genes in relation to one another?Given the following pedigree (note that C7C, M4C, N2X, H6C, G9X, J1C, B8X, and P2X are the names of animals): For a specific example, you might assume that four members of this pedigree are albinos: the woman in the first generation, her second daughter (the mother of individuals 5, 6, 7, and 8), and individuals 4 and 11 in the third generation. Now, assume that you are a genetic counselor and that individuals 6 and 12 in the third generation of this pedigree come to you and ask, “What is the probability that if we marry and have a family, an albino child will be born to us?” The counselor must determine the probability that individuals 6 and 12 are heterozygous carriers of the recessive gene for albinism. The counselor must also consider the probability of two heterozygous carriers producing a homozygous recessive child. First of all, the mother of individual 6 is an albino (cc), which means that 6 must be (probability = 1 or 100%) a heterozygote. The father of individual 12 must be heterozygous (Cc) since his mother is an albino. Although individual 12 is not an albino, he has a ½ chance of…
- . The pedigree below was obtained for a rare kidney disease.a. Deduce the inheritance of this condition, stating your reasons. b. If persons 1 and 2 marry, what is the probability that their first child will have the kidney disease?Given the following pedigree: Is the trait autosomal or sex-linked? Is the trait dominant or recessive? Based only on the information given, what is the probability that I-2 is heterozygous? Give the genotypes of individuals II-3, II-4. What is the probability that individual III-1 is purebreeding?The genotype of EB27 and EB67 are unknown. Based on pedigree, what are the most likely genotype of each individual?
- A series of three-point testcrosses is made to determine the genetic map order of seven linked allele pairs: A/a, B/b, G/g, H/h, Q/q, R/r, and Y/y.From each cross between a triply heterozygous parent listed below, two recombinant classes were noticed as the least frequent among all 8 progeny classes, and are listed at the right in the table. A. For each testcross write the genotype of the F1 heterozygous parent. F1 Parental Phenotype Least frequent F2 Phenotype 1.AHB&ahb AHb & ahB 2.RYh&ryH RYH & ryh 3.BhY&bHy Bhy & bHY 4.qYB&Qyb qYb & QyB 5.AbQ&aBq Abq & aBQ 6.ghR&GHr ghr & GHR B. Write the unified map order of these genes, showing your reasoning.In a three-point testcross such as this one, why aren’t the F1 and the tester considered to be parental in calculating recombination? (They are parents in one sense.). A corn geneticist has three pure lines of genotypes a/a ; B/B ; C/C, A/A ; b/b ; C/C, and A/A ; B/B ; c/c. All the phenotypes determined by a, b, and c will increase the market value of the corn; so, naturally, he wants to combine them all in one pure line of genotype a/a ; b/b ; c/c. a. Outline an effective crossing program that can be used to obtain the a/a ; b/b ; c/c pure line. b. At each stage, state exactly which phenotypes will be selected and give their expected frequencies. c. Is there more than one way to obtain the desired genotype? Which is the best way?Assume independent assortment of the three gene pairs. (Note: Corn will self or cross-pollinate easily.