This pedigree below represents a disease that is very rare in the human population and completely penetrant. Answer the two questions below.a.) What are the two possible modes of inheritance?b.) Which one is most likely (probable)? Briefly explain your answer for part b.Eor the toplhar press Al T+F10 (PCL ar ALT+EN+F10 (Mar)

Name: This pedigree below represents a disease that is very rare in the hum
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Description: This pedigree below represents a disease that is very rare in the human population and completely penetrant. Answer the two questions below.a.) What are the two possible modes of inheritance?b.) Which one is most likely (probable)? Briefly explain y

Introduction Pedigree Analysis: this is the new approach to study the inheritance pattern in the…

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Biology

This pedigree below represents a disease that is yery.rare in the human population and comeletey cenetrant. Ansver the two questions belov a) What are the tvo possible modes of inheritance? b.) Which one is most likely (probable)? Briefy explain your answer for part b.

This pedigree below represents a disease that is yery.rare in the human population and comeletey cenetrant. Ansver the two questions belov a) What are the tvo possible modes of inheritance? b.) Which one is most likely (probable)? Briefy explain your answer for part b.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 3QP: Pedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the...

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a. On the basis of this pedigree, what is the most likely mode of inheritance for the disease? Explain your reasoning. b. Based your answer to part a, give the most likely genotypes for all family members in the pedigree.
The pedigree below shows that inheritance of a disease that is caused by a late onset, dominant, autosomal mutation that is rare, but only 50% penetrant. The gene that is mutated in the disease is linked at a distance of 10 cm to a microsatellite marker that has alleles numbered 1, 2, and 3. The marker alleles detected in each individual are indicated below. What is the probability that individual A will develop the disease? Explain using an illustration of this occurs.
Below is a pedigree of a human genetic disease in which solid color indicates affected individuals. Assume that the disease is caused by a gene that can have the alleles A or a. a) Based on this pedigree, what is the most likely mode of inheritance? b) What is/are the possible genotype/s of person 1? c) What is/are the possible genotype (s) of person 4 ? Explain your answers.
. The pedigree below was obtained for a rare kidney disease.a. Deduce the inheritance of this condition, stating your reasons. b. If persons 1 and 2 marry, what is the probability that their first child will have the kidney disease?
A rare disease is found in a family as shown in the pedigree below. Assuming complete penetrance, answer the following questions below. Q1) What is the most likely mode of inheritance for this pedigree? Please explain your answer.
The pedigree below is of a rare single gene disease. Given the pedigree shown below, what is the most likely pattern of inheritance for this disease? Explain your answer. Note that closed symbols are for individuals affected by the disease and open symbols are unaffected individuals (limit 3-4 sentences).
A family is tested for spinal muscular atrophy, an autosomal recessive disease, using RFLP. The normal gene can be digested with a specific enzyme, while the mutant cannot. According to the pedigree below, which of the following is most likely the RFLP results?
Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?
Which members of the pedigree could have been carriers, and which might have been the source of the mutation?
Hemophilia and color blindness are both recessive conditions caused by genes on the X chromosome. To calculate the recombination frequency between the two genes, you draw a large number of pedigrees that include grandfathers with both hemophilia and color blindness, their daughters (who presumably have one chromosome with two normal alleles and one chromosome with two mutant alleles), and the daughters sons. Analyzing all the pedigrees together shows that 25 grandsons have both color blindness and hemophilia, 24 have neither of the traits, 1 has color blindness only, and 1 has hemophilia only. How many centimorgans (map units) separate the hemophilia locus from the locus for color blindness?
The pedigree pictured is of an extended family where a large percentage of family members develop colon cancer at an early age. In this family, individuals either get colon cancer before the age of 16, or they don’t get it at all. a) Based on the information you have been given, what evidence, if any, suggests an inherited contribution to the development of this disease? b) You take a medical history of all 33 people in the pedigree and discover that a large percentage drink a special coffee on a daily basis, while others do not. The individuals who do not drink coffee are I-1, II-2, II-4, II-9, III-7, III-13, IV-1, and IV-3. Could drinking this special coffee play a role in colon cancer? Explain.
Given the following pedigree added. What questions are true and false?