The imidazole ring on Histamine has a pKa of 6.5.  What is the %ionization of this group at pH 8.2?

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter27: Amino Acids And Proteins
Section: Chapter Questions
Problem 27.33P
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The imidazole ring on Histamine has a pKa of 6.5.  What is the %ionization of this group at pH 8.2?

 

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