The inhibitor X prevents coenzyme Q (Q) from participating in electron transfer in the electron transport chain. (a) Will the presence of X prevent electrons from N ADH from passing through the electron trans- port chain? Explain why or why not. (b) Compound Y is a non-physiological reducing agent capable of directly reducing cytochrome c1 in Complex III. Would oxygen consumption resume upon the addition of compound Y to mitochondria inhibited by inhibitor X? Be sure to explain your answer.
The inhibitor X prevents coenzyme Q (Q) from participating in electron transfer in the electron transport chain. (a) Will the presence of X prevent electrons from N ADH from passing through the electron trans- port chain? Explain why or why not. (b) Compound Y is a non-physiological reducing agent capable of directly reducing cytochrome c1 in Complex III. Would oxygen consumption resume upon the addition of compound Y to mitochondria inhibited by inhibitor X? Be sure to explain your answer.
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter20: Electron Transport And Oxidative Phosphorylation
Section: Chapter Questions
Problem 11P
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Question
The inhibitor X prevents coenzyme Q (Q) from participating in electron transfer in the electron
transport chain.
(a) Will the presence of X prevent electrons from N ADH from passing through the electron trans-
port chain? Explain why or why not.
(b) Compound Y is a non-physiological reducing agent capable of directly reducing cytochrome
c1 in Complex III. Would oxygen consumption resume upon the addition of compound Y to
mitochondria inhibited by inhibitor X? Be sure to explain your answer.
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