The mutations found in the CF gene that result in cystic fibrosis are recessive because.. (Justify your answer) a) CF is fatal and if the alleles that caused CF were dominant it would not be inherited b) The CF mutations that occur result in no protein being produced and this is the only possible way for the mutations to be recessive c) Normal or near normal cellular function can occur from the protein produced by the normal allele in a carrier d) CF mutations only result in a protein that has normal function if there is also a normal CF protein in the cell

The mutations found in the CF gene that result in cystic fibrosis are recessive because.. (Justify your answer) a) CF is fatal and if the alleles that caused CF were dominant it would not be inherited b) The CF mutations that occur result in no protein being produced and this is the only possible way for the mutations to be recessive c) Normal or near normal cellular function can occur from the protein produced by the normal allele in a carrier d) CF mutations only result in a protein that has normal function if there is also a normal CF protein in the cell

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Description: The mutations found in the CF gene that result in cystic fibrosis are recessive because.. (Justify your answer) a) CF is fatal and if the alleles that caused CF were dominant it would not be inheritedb) The CF mutations that occur result in no protei

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

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DNA sequencing of your own two β-globin genes (one from each of your two Chromosome 11s) reveals a mutation in one of the genes. given this information alone, should you worry about being a carrier of an inherited disease that could be passed on to your children? What other information would you like to have to assess your risk?
Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior history of the disease. Consider the following pedigree (the darkly colored symbols represent affected individuals): a. Circle the individual(s) in which the mutation most likely occurred. b. Is the person who is the source of the mutation affected by retinoblastoma? Justify your answer. c. Assuming that the mutant allele is fully penetrant, what is the chance that an affected individual will have an affected child?
Why Recessive CF disease alleles either produce no CFTR or produce nonfunctional or less functional versions of the protein?
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