The reaction catalyzed by citrate syn- thase, shown on the right, is the first step of the TCA cycle. In glycolysis, two key reactions to produce ATP occur because an unfavorable reaction is coupled to another reaction that is thermodynamically favorable. The reaction catalyzed by citrate synthase, shown on the right, is similarly coupled to an unfavorable reac- tion in the TCA cycle. Write the unfavorable reaction using structural formulas and write the key step that drives the two coupled reactions forward. What is the overall AGO of the coupled reactions? CH3-C 0=0 + S-CoA Acetyl-CoA 0-C-COO™ CH₂-COO™ Oxaloacetate H₂O COA-SH citrate synthase CH₂-C C HỌC—COO 0 CH₂-COO™ Citrate AG'= -32.2 kJ/mol

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Chapter21: Photosynthesis
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The reaction catalyzed by citrate syn-
thase, shown on the right, is the first step of the TCA
cycle. In glycolysis, two key reactions to produce ATP
occur because an unfavorable reaction is coupled to
another reaction that is thermodynamically favorable.
The reaction catalyzed by citrate synthase, shown on
the right, is similarly coupled to an unfavorable reac-
tion in the TCA cycle. Write the unfavorable reaction
using structural formulas and write the key step that
drives the two coupled reactions forward. What is the
overall AG'o of the coupled reactions?
CH3-C
>=0
+
S-COA
Acetyl-CoA
0-C-COO-
CH₂-COO
Oxaloacetate
H₂O COA-SH
J
citrate
synthase
CH₂-C
HỌ—C—COO
SO
CH₂-COO
Citrate
AG'= -32.2 kJ/mol
Transcribed Image Text:The reaction catalyzed by citrate syn- thase, shown on the right, is the first step of the TCA cycle. In glycolysis, two key reactions to produce ATP occur because an unfavorable reaction is coupled to another reaction that is thermodynamically favorable. The reaction catalyzed by citrate synthase, shown on the right, is similarly coupled to an unfavorable reac- tion in the TCA cycle. Write the unfavorable reaction using structural formulas and write the key step that drives the two coupled reactions forward. What is the overall AG'o of the coupled reactions? CH3-C >=0 + S-COA Acetyl-CoA 0-C-COO- CH₂-COO Oxaloacetate H₂O COA-SH J citrate synthase CH₂-C HỌ—C—COO SO CH₂-COO Citrate AG'= -32.2 kJ/mol
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