The structure below is ibuprofin with weak acid pka 4.4 LOH Give the protonation state of ibuprofen in the stomach and draw the structure in (pH ~ 2)? Give the protonation state of ibuprofen in the bloodstream and draw the structure in (pH 7.3)? Blood is a buffer of bicarbonate and carbonic acid. Draw the curved arrow mechanism for the acid-base reaction that occurs between ibuprofen and bicarbonate in the bloodstream.

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Chapter1: Chemical Foundations
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The structure below is ibuprofin with weak acid pka 4.4
HO
Give the protonation state of ibuprofen in the stomach and draw the structure in (pH ~ 2)?
Give the protonation state of ibuprofen in the bloodstream and draw the structure in (pH 7.3)?
Blood is a buffer of bicarbonate and carbonic acid. Draw the curved arrow mechanism for the acid-base
reaction that occurs between ibuprofen and bicarbonate in the bloodstream.
Transcribed Image Text:The structure below is ibuprofin with weak acid pka 4.4 HO Give the protonation state of ibuprofen in the stomach and draw the structure in (pH ~ 2)? Give the protonation state of ibuprofen in the bloodstream and draw the structure in (pH 7.3)? Blood is a buffer of bicarbonate and carbonic acid. Draw the curved arrow mechanism for the acid-base reaction that occurs between ibuprofen and bicarbonate in the bloodstream.
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