Understanding why these receptors are present when they are not supposed to be is important in finding new treatments for Cushing's syndrome. When the sequences for the promoters for the receptor genes were analyzed there was no common sequences found. This led to the theory that the loss of methylation of cytosine in the promoters of these genes was leading to their inappropriate expression. How could the loss of cytosine methylation lead to overexpression of the receptor genes? O a. Increased histone acetyltransferase activity O b. Decreased histone deacetylase activity Oc Decreased histone acetyltransferase activity O d. Increased histone deacetylase activity

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 21QP: Transcriptional regulators are proteins that bind to promoters (the 5-flanking regions of genes) to...
icon
Related questions
Topic Video
Question
Understanding why these receptors are present when they are not supposed to be is important in finding new
treatments for Cushing's syndrome. When the sequences for the promoters for the receptor genes were
analyzed there was no common sequences found. This led to the theory that the loss of methylation of
cytosine in the promoters of these genes was leading to their inappropriate expression.
How could the loss of cytosine methylation lead to overexpression of the receptor genes?
O a. Increased histone acetyltransferase activity
O b. Decreased histone deacetylase activity
Oc Decreased histone acetyltransferase activity
O d. Increased histone deacetylase activity
Transcribed Image Text:Understanding why these receptors are present when they are not supposed to be is important in finding new treatments for Cushing's syndrome. When the sequences for the promoters for the receptor genes were analyzed there was no common sequences found. This led to the theory that the loss of methylation of cytosine in the promoters of these genes was leading to their inappropriate expression. How could the loss of cytosine methylation lead to overexpression of the receptor genes? O a. Increased histone acetyltransferase activity O b. Decreased histone deacetylase activity Oc Decreased histone acetyltransferase activity O d. Increased histone deacetylase activity
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Gene expression
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co…
Human Heredity: Principles and Issues (MindTap Co…
Biology
ISBN:
9781305251052
Author:
Michael Cummings
Publisher:
Cengage Learning