Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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Solution
Sodium tetrahydridoborate (previously referred to as metal borohydride) has the formula NaBH4, and contains the BH4- particle. That particle acts because the reducer.
There area unit many quite alternative ways of closing this reaction. 2 attainable variants (there area unit many others!) are:
The reaction is distributed in answer in water to that some caustic soda has been additional to create it alcalescent. The reaction produces associate degree intermediate that is regenerate into the ultimate product by addition of a dilute acid like acid
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