Briefly answer the following Questions1. What is the commercial use of ibuprofen?2. What are the important criteria of a good resolving agent in the resolution of ibuprofen?3. In particular why is (S)-methylbenzylamine a suitable resolving agent for ibuprofen? H2SO4NH3OH(S)-(+)-ibuprofen(not water soluable)(S,S) SaltHSO4NH3ammonium salt(water soluable) CH3NH3NH2CH3(S,S) Salt- Insoluable in Aqueous SolutionForms Precipitate+OHRacemic-(+)-Ibuprofen(S)-(-)-methy lbenzyl amineCHaNH3(R,S) Salt- Soluable in Aqueous Solution

1) Commercial use: It is used to relieve pain from various conditions like - headache,…

What is the commercial use of ibuprofen? 2. What are the important criteria of a good resolving agent in the resolution of ibuprofen? 3. In particular why is (S)-methylbenzylamine a suitable resolving agent for ibuprofen?

What is the commercial use of ibuprofen? 2. What are the important criteria of a good resolving agent in the resolution of ibuprofen? 3. In particular why is (S)-methylbenzylamine a suitable resolving agent for ibuprofen?

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter31: Immunochemistry

Section: Chapter Questions

Problem 31.75P

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Question

Briefly answer the following Questions

1. What is the commercial use of ibuprofen?

2. What are the important criteria of a good resolving agent in the resolution of ibuprofen?

3. In particular why is (S)-methylbenzylamine a suitable resolving agent for ibuprofen?

H2SO4
NH3
OH
(S)-(+)-ibuprofen
(not water soluable)
(S,S) Salt
HSO4
NH3
ammonium salt
(water soluable)

CH3
NH3
NH2
CH3
(S,S) Salt- Insoluable in Aqueous Solution
Forms Precipitate
+
OH
Racemic-(+)-Ibuprofen
(S)-(-)-methy lbenzyl amine
CHa
NH3
(R,S) Salt- Soluable in Aqueous Solution

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