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in a village where hte proportion of individuals who are susceptible to malaria (genotype hbA/hbA) is 0.53 and hte population is asssumed to be at hardy weingberg equalibrium what is the expected freqency of the HbS alle? hint what is the genotype of people with sickle cell disease and how is that genotype represneted in the hardy weinberg equation
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- In a population where the proportion of individuals who are suspects to malaria (genotype HbA/HbA) is 0.31, and the population is assumed to be at Hardy Weinberg equilibrium what proportion of the population should be heterozygous HbA/HbS?in a village where the proportion of individuals who are susceptible to malaria (genotype hba/hba) is 0.53 and the population is assumed to be at hardy weinberg equallibruim what proportion of the population should be hetrozygous hba /hbsAn allele of the G6PD gene acts in a recessive manner to cause sensitivity to fava beans, resulting in ahemolytic reaction (lysis of red blood cells) afteringestion of the beans. The same allele also confersdominant resistance to malaria. The heterozygote hasan advantage in a region where malaria is prevalent.Will the equilibrium frequency (qe) be the same foran African and a North American country? Whatfactors affect qe?
- While studying the frequency of sickle-cell disease ("sickle cell anemia") in a population living in sub-Saharan Africa, you obtain the following data from a sample of n= 100 people (note that I chose a simpler system for identifying the alleles rather than using "Hb S" for sickle cell allele), which is the actual name and what you used in lab). What is the frequency of the sickle cell allele (b) in the sample below from a human population? Sample Data BB-60 individuals (No sickle cell disease) Bb-30 individuals (No sickle cell disease) bb-10 individuals (Sickle cell disease) 1. 0.25 2. 0.10 3. 0.35 4. 0.60 5. 0.20The prevalence (frequency) of sickle-cell disease in Canada is quite low, affecting 1/3800 individuals. However, in some African populations 1/25 individuals are affected by sickle-cell disease. The difference in frequency of this allele within the differing populations has to do with the adaptation pressures that exist in the different environments. Individuals with the heterozygous genotype have a survival advantage in environments where the disease malaria is prevalent as the presence of this mutant allele leads to resistance to malaria. Therefore, the sickle-cell disease tends to be more frequent in environments where the malaria parasite is most common. Question: Explain why the sickle-cell disease remains frequent in some populations while it exists in very low frequency in other populations.Sickle-cell anemia is a recessive disease that afflicts approximately 1 in 12 African Americans, meaning that the frequency of ss homozygotes is 0.09. Assuming the African American population is in Hardy-Weinberg equilibrium, what is the frequency of Ss carriers in this population?
- Panthers are also susceptible to a respiratory infection [feline calicivirus]. Individuals in a population, who are homozygous dominant or heterozygous for genes encoding parasite or pathogen resistance, are more likely to resist an infection or parasite. Currently, population estimates of the Florida panther range from 100 – 160 individuals. Let’s assume that the population equals 160. During a particularly bad calicivirus outbreak, 40 Florida panthers die as a result of the infection. Using this information, answer the following questions utilizing the Hardy – Weinberg equation when necessary. What is the most likely genotype of the affected panthers that died from the respiratory infection? Use the letter “A” for your symbol. 2. What percentage of the population is most likely resistant to the calicivirus infection?Panthers are also susceptible to a respiratory infection [feline calicivirus]. Individuals in a population, who are homozygous dominant or heterozygous for genes encoding parasite or pathogen resistance, are more likely to resist an infection or parasite. Currently, population estimates of the Florida panther range from 100 – 160 individuals. Let’s assume that the population equals 160. During a particularly bad calicivirus outbreak, 40 Florida panthers die as a result of the infection. Using this information, answer the following questions utilizing the Hardy – Weinberg equation when necessary. What is the most likely genotype of the affected panthers that died from the respiratory infection? Use the letter “A” for your symbol. What percentage of the population is most likely resistant to the calicivirus infection? Using the information given for the inheritance of pathogen resistance, construct a Punnett square crossing a heterozygous individual to a homozygous…Despite their excellent hygienic practices, the Kelatavicla lab experiences a devastating bacterial infection in their mouse population in 2012. Given the conditions in column B, predict what will happen to the frequency of the R allele over the years (increase, decrease, or remain the same) if the outbreak is not contained?
- Describe the effect of malaria on the frequency of the HbS allele in areas where malaria is common:In areas with malaria, which individual would survive better and leave more offspring- an individual with two HbA alleles or an individual with one HbA allele and one HbS allele? Given this, would you expect the HbS allele to be common or rare in populations living with malaria?Which of the following is TRUE of the relationship between sickle cell anemia and malaria? Choose all that apply. Group of answer choices A person with malaria is more susceptible to sickle cell anemia. The sickle cell allele provides protection against malaria. In Boston, there is no advantage to the sickle cell allele. One would expect that if the frequency of malaria were to increase in an area, so would the frequency of sickle cell anemia.In a human population of 1000, 840 are tongue rollers (360 TT and 480 Tt), and 160 are not tongue rollers (tt). What is the frequency of the dominantallele (T) in the population?