What is the first step in planning a retrosynthesis of the amine shown below.1st retrosynthesis step?Carbon heteroatom (C-X) disconnection between the carbon-nitrogen bondB Functional group interconversion to an imineC Functional group interconversion to an amideD Reductive elimination

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Answered: What is the first step in planning a…

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter23: Addition To A Carbonyl

Section: Chapter Questions

Problem 25E

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Similar questions

Rank the following compounds in order of increasing basicity: I. p-nitroaniline III. N-methylaniline II. p-aminobenzaldehyde IV. p-methylaniline
Show how you can synthesize the following tertiary amine three different ways, each using a different secondary amineand adding the final substituent by(a) reductive amination (3 ways). (b) acylation–reduction (3 ways).
What kinds of halides cannot be used to alkylate an amine? Why not? a.Tertiary halides form alkenes on elimination. b.Aryl halides unless activated by electron-withdrawing groups c.Halides with beta-alkyl groups are sterically hindered. d. all of the above
based on this video: on Hinsberg Test Tests for Amines - MeitY OLabs (8.5min) https://www.youtube.com/watch?v=j5jgMUWri8U Write the reaction (two-step, in skeletal) of each test amine when tested in the Hinsberg Test.
Several additional amine syntheses are effectively limited to making primary amines. The reduction of azides and nitrocompounds and the Gabriel synthesis leave the carbon chain unchanged. Formation and reduction of a nitrile adds onecarbon atom. Show how these amine syntheses can be used for the following conversions.(a) allyl bromide S allylamine (b) ethylbenzene S p@ethylaniline
Show how Gabriel syntheses are used to prepare the following amines. g@aminobutyric acid
Each pair of compounds below can be separatedusing acid/base extraction. Provide the common acid or base that could be used to effect the separation. Amines can be converted into ammonium salts using acid, but neutral amines are very weak acids (pKa~ 35)and thus cannot be extracted by an aqueous base.
Place the binders below in descending order of acidity (pi) and justify your choice: CH3CN; (C2H5)2O; PCl3; As(C6H5)3; (C2H5)3N
What does the reaction of 4-Chloropentan-2-amine reacted with excess CH3l, Ag2O produce? O Hofmann product only O Zaitsev product only O Both Hofmann and Zaitsev products Equal distribution
Several additional amine syntheses are effectively limited to making primary amines. The reduction of azides and nitrocompounds and the Gabriel synthesis leave the carbon chain unchanged. Formation and reduction of a nitrile adds onecarbon atom. Show how these amine syntheses can be used for the following conversions. (c) 1@bromo@3@phenylheptane S 3@phenylheptan@1@amine (d) 1@bromo@3@phenylheptane S 4@phenyloctan@1@amine
Which or which of the statements given below is correct. I) Maleic anhydride is a carboxylic acid derivative and its reaction with water is a reduction reaction. II) Fumaric acid and maleic acid are stereoisomers of each other III) Since fumaric acid has a more stable structure than maleic acid, its boiling point is higher. A. Solo I B. I and III C. II and III D. I, II, III E. Solo III
N-Nitroso amines are stabilized by electron delocalization. Write the two most stable resonance contributors of N-nitrosodimethylamine, (CH3)2NNO.

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What is the first step in planning a retrosynthesis of the amine shown below. 1st retrosynthesis step? Carbon heteroatom (C-X) disconnection between the carbon-nitrogen bond B Functional group interconversion to an imine C Functional group interconversion to an amide D Reductive elimination