What is the penetrance of this trait? i.e., What is the ratio between the number of individuals in the pedigree who display the trait (numerator) and the number of individuals you know from the pedigree must have the trait-determining genotype (denominator)?

What is the penetrance of this trait? i.e., What is the ratio between the number of individuals in the pedigree who display the trait (numerator) and the number of individuals you know from the pedigree must have the trait-determining genotype (denominator)?

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Description: What is the penetrance of this trait? i.e., What is the ratio between the number of individuals in the pedigree who display the trait (numerator) and the number of individuals you know from the pedigree must have the trait-determining genotype (denom

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 5QP: Analysis of Autosomal Recessive and Dominant Traits a. What pattern of inheritance is suggested by...

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Question: This is a normal 3 point test cross, except that instead of regular phenotypes, you are looking at DNA markers on a gel. One parent, according to the gel, is heterozygous at each marker. The other parent is homozygous for each marker. (Again, this means it is a test cross: AaEeHh x AAEEHH --but don't be confused by that, because these are not "dominant" and "recessive" per se; the phenotype is just a band on a gel). For each offspring, figure out its genotype (homozygous or heterozygous for each gene. Then, figure that one parent made only AEH gametes, so you can cross that out if it helps.) Then treat it pretty much the same as a 3 point test cross.
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Analysis of X-Linked Dominant and Recessive Traits As a genetic counselor investigating a genetic disorder in a family, you are able to collect a four-generation pedigree that details the inheritance of the disorder in question. Analyze the information in the pedigree to determine whether the trait is inherited as: a. autosomal dominant b. autosomal recessive c. X-linked dominant d. X-linked recessive e. Y-linked
Analysis of Autosomal Recessive and Dominant Traits a. What pattern of inheritance is suggested by the following pedigree? b. For genotype assignment, assume that the pedigree is for an autosomal dominant trait and that the affected male in the first generation is heterozygous. Assign genotypes to all other individuals in the pedigree.
Question 1: In tomatoes, round fruit (O) is dominant to oblong fruit (o). Write as much as possible of the genotypes of: (A) A plant from a homozygous round-fruited stock (B) A plant from an oblong strain (C) A round-fruited plant which resulted from a testcross (D) A oblong-fruited plant which resulted from the cross of two round-fruited ones.
Question 6: If individuals IV-4 and IV-5 mate and have a child, what is the probability that the child will have the genetic condition? Assume people mating into the pedigree do not carry the abnormal allele unless information given in the pedigree suggests otherwise. Write the probability as a fraction without any spaces, answers given as a decimal will be marked incorrect. (For example write your answer as 5/72 – note that is NOT the correct answer).
Question 6 Albinism is caused by an autosomal recessive allele that interferes with skin pigmentation in mammals. Two normally pigmented human parents already have an albino boy. They plan to continue to have children until they get a girl. Some or all of this information is important for each of the questions below. a) What is the probability that their next child (currently unborn) will be a girl with albinism? Explain your reasoning. b) What is the probability their first female child will be albino? Explain your reasoning. c) The answer to part (b) is different (and, yes, the answer is different) from the answer to part (a). Explain why. (Hint: it has something to do with the underlined words.)
Someone please help with each question, they are all about the same pedigree