What is/are the attributes that make nucleotide excision repair (NER) and base excision repair (BER) similar and/or different from each other? Select the correct response: The NER pathway is the only one that can remove DNA lesions in the strand regardless of their size which is followed by attaching the correct strand, then sealed by a DNA ligase. They both use the enzyme DNA glycosylases that recognizes the damaged DNA segments and proceed with repairing the faulty base in the strand. They differ NER only repairs purine bases while BER repairs pyrimidine bases. They both remove the damaged parts of the DNA where the BER pathway corrects only the identified damaged bases which are usually non-bulky lesions. The NER pathway, on the other hand, repairs the damage by removal of bulky DNA adducts which is a short-single stranded DNA segment. They both utilize the enzyme photolyase to reverse the damages created by the faulty section of the DNA. They both remove the damaged parts of the DNA where the BER pathway corrects only the identified damaged bases which are usually bulky lesions. The NER pathway, on the other hand, repairs the damage by removal of non-bulky DNA adducts which is a short-single stranded DNA segment.
What is/are the attributes that make nucleotide excision repair (NER) and base excision repair (BER) similar and/or different from each other? Select the correct response: The NER pathway is the only one that can remove DNA lesions in the strand regardless of their size which is followed by attaching the correct strand, then sealed by a DNA ligase. They both use the enzyme DNA glycosylases that recognizes the damaged DNA segments and proceed with repairing the faulty base in the strand. They differ NER only repairs purine bases while BER repairs pyrimidine bases. They both remove the damaged parts of the DNA where the BER pathway corrects only the identified damaged bases which are usually non-bulky lesions. The NER pathway, on the other hand, repairs the damage by removal of bulky DNA adducts which is a short-single stranded DNA segment. They both utilize the enzyme photolyase to reverse the damages created by the faulty section of the DNA. They both remove the damaged parts of the DNA where the BER pathway corrects only the identified damaged bases which are usually bulky lesions. The NER pathway, on the other hand, repairs the damage by removal of non-bulky DNA adducts which is a short-single stranded DNA segment.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:What is/are the attributes that make nucleotide excision repair (NER) and base excision repair (BER)
similar and/or different from each other?
Select the correct response:
The NER pathway is the only one that can remove DNA lesions in the strand regardless of
their size which is followed by attaching the correct strand, then sealed by a DNA ligase.
They both use the enzyme DNA glycosylases that recognizes the damaged DNA segments
and proceed with repairing the faulty base in the strand. They differ NER only repairs purine
bases while BER repairs pyrimidine bases.
They both remove the damaged parts of the DNA where the BER pathway corrects only the
identified damaged bases which are usually non-bulky lesions. The NER pathway, on the
other hand, repairs the damage by removal of bulky DNA adducts which is a short-single
stranded DNA segment.
They both utilize the enzyme photolyase to reverse the damages created by the faulty section
of the DNA.
They both remove the damaged parts of the DNA where the BER pathway corrects only the
identified damaged bases which are usually bulky lesions. The NER pathway, on the other
hand, repairs the damage by removal of non-bulky DNA adducts which is a short-single
stranded DNA segment.
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