Which of the following is true of ribosome rescue? (C & E wrong) A. The process produces a protein that is tagged for degradation. B. Proteases enter the A-site of the ribosome to degrade the C-terminus of the synthesized peptide. C. A partially translated mRNA becomes fully degraded before it can be translated further. D. No protein is produced in the process. E. Stalled ribosomes are released in the absence of a stop codon.

Which of the following is true of ribosome rescue? (C & E wrong) A. The process produces a protein that is tagged for degradation. B. Proteases enter the A-site of the ribosome to degrade the C-terminus of the synthesized peptide. C. A partially translated mRNA becomes fully degraded before it can be translated further. D. No protein is produced in the process. E. Stalled ribosomes are released in the absence of a stop codon.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter9: Gene Expression And Gene Regulation

Section: Chapter Questions

Problem 11QP: Briefly describe the function of the following in protein synthesis. a. rRNA b. tRNA c. mRNA

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A rare mutation can result in eukaryotic cells that causes a failure in the cell to synthesize the Signal Recognition Particle (SRP). Failure to make the SRP would impact protein synthesis by ________ . A. Preventing transition of bound ribosomes to free ribosomes B. Preventing binding of ribosomes to the rough ER during synthesis of proteins with a signal sequence C. Preventing export of mRNA out of the nuclear envelope D. Preventing binding of ribosomes to the smooth ER during synthesis of proteins with a signal sequence
If a cell's DNA was mutated such that it lost the promoter of a gene, you would expect: a. That ribosomes wouldn’t bind to that gene b. No effect since the promoter doesn't have any coding information for the amino acids in the polypeptide c. Ribosomes would never stop translating that gene d. Transcription factors for that gene would no longer bind to activate expression of that gene e. tRNA would no longer bind to the codons of that gene
When would a ribosome bind to a promoter sequence? A) It wouldn't. A promoter is a DNA sequence, and ribosomes don't bind to DNA. B) When the ribosome needs to transcribe the gene that that promoter controls. C) When the ribosome is translating the DNA sequence of a gene. D) When there is a start codon (AUG) in the promoter sequence. .
The binding of iron regulatory protein (IRP) to the iron response element (IRE) in the 5′ region of the ferritin mRNA results in the a. inhibition of translation of the ferritin mRNA. b. stimulation of translation of the ferritin mRNA. c. degradation of the ferritin mRNA. d. both a and c.
Which of the following statements are correct? explain your answers.A. An individual ribosome can make only one type of protein.B. All mRNAs fold into particular three-dimensional structures that are required for their translation. C. the large and small subunits of an individual ribosome always stay together and never exchange partners.D. ribosomes are cytoplasmic organelles that are encapsulated by a single membrane.E. Because the two strands of DNA are complementary, the mRNA of a given gene can be synthesized using either strand as a template.F. An mRNA may contain the sequence ATTGACCCCGGTCAA.G. the amount of a protein present in a cell depends on its rate of synthesis, its catalytic activity, and its rate of degradation.
A protein is normally secreted from the cell. A team of scientists attempts to redirect this protein to the inside of the nucleus by mutating the sequence of the gene. Unfortunately, after this mutation, the protein is no longer secreted, but it is now localized to the cytosol and not the nucleus. Briefly answer the two questions below: a. Identify the sequence that was mutated by the scientists and explain your reasoning. b. What additional mutation must be made by the scientists to redirect this protein to the nucleus? Explain your reasoning
Number the following steps of protein synthesis in the order in which they occur, starting with 1 and ending with 9.a. _____ The stop codon is reached, and the polypeptide is released.b. _____ The small ribosomal subunit finds the start codon, and the large ribosomal subunit joins.c. _____ The end of the gene is reached, and the pre-mRNA is released and then edited.d. _____ The transcription factor binds the promoter.e. _____ The protein is folded and modified to become functional.f. _____ RNA polymerase builds the mRNA transcript.g. _____ mRNA and initiator tRNA bind the small ribosomal subunit.h. _____ New tRNA molecules are brought into the A site successively, and the peptide chain of the tRNA in the P site is joined to the amino acid of the tRNA in the A site.i. _____ mRNA exits the nucleus via a nuclear pore.
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According to the adaptor hypothesis, is each the following statementstrue or false?A. The sequence of an anticodon in a tRNA directly recognizes acodon sequence in mRNA, with some allowance for wobble.B. The amino acid attached to the tRNA directly recognizes acodon sequence in mRNA.C. The amino acid attached to the tRNA affects the binding of thetRNA to a codon sequence in mRNA.
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What process is the P site in a ribosome most closely associated with? a. Binds the tRNA molecule carrying the next needed amino acid to the mRNA strand b. Transcription of DNA to RNA c. Release of a tRNA molecule from a ribosome d. Anchoring of the tRNA holding the growing polypeptide