Why are SGLT1 inhibitors drugs able to lower blood glucose and why do they cause diarrhea?

Q: Does Inactivating the PCSK9 Enzyme Lower LDL Levels?

A: Introduction  PCSK-9 (Proprotein convertase subtilisin-like kexin type 9) is newly discovered serine…

Q: Why do glucose needs to be injected to a patient through intravenous injection?

A: Glucose is sugar which provides energy to the body. It is naturally present in body fluids and is…

Q: Why is it that intravenous infusion of glucose is given to a patient?

A: The administration of medication is an essential activity for the recovery from the illness. The…

Q: Would the absorption of water into absorptive cells be increased or decreased following cyanide…

A: Cyanide is a deadly chemical that acts very rapidly. It can exist in many forms. The cyanide group…

Q: What is the pharmacodynamics that elevates the INR in a patient taking Warfarin and Motrin together?

A: Introduction:-  In general, you should avoid taking ibuprofen (also known as Advil, Motrin, and…

Q: Describe the mechanisms controlling the pancreatic secretion ofHCO32 and enzymes?

A: The pancreas is a glandular organ present in the abdominal cavity of the vertebrate. It has both…

Q: Why Do Diabetics Excrete Glucose in Their Urine?

A: Diabetes is a physiological condition that leads to too much sugar in the blood causing high blood…

Q: Name the substrates for the following enzymes:  a) trypsinb) amylasec) pepsind) lipase

A: Chemical digestion of nutrients occurs in the digestive system. Several digestive glands and organs…

Q: Under what circumstances might the appetite-suppressing action of leptin be counterproductive?

A: Leptin is the specific hormone to control hunger. it is made up of adipose cell and the cells of…

Q: What happens to the triglyceride concentrations in the plasma and inadipose tissue after…

A: The drug administered in the body cause-affect triglyceride concentration. The two main…

Q: at is the relationship between fructose and de novo lipogenesis? s glucose also cause this process…

A: Denovo lipogenesis converts excess carbohydrate into fatty acids that are then esterified as storage…

Q: Alpha-glucosidase inhibitors are contraindicated in all of the following cases, except:A. Diabetic…

A: Alpha glucosidase inhibitors are generally used in the treatment of type-II diabetes. Alpha…

Q: What are the advantages of intravenous infusion of glucose than other injection like subcutaneous…

A: Routes of drug administration is the path by which the drugs, fluids or other medicines are…

Q: Discuss the toxic effects of the ammonium ion and excess bicarbonate ion. What is the effect of…

A: Living organisms excrete the excess nitrogen resulting from the metabolic breakdown of amino…

Q: How does the amino acid substitution and amino acid chain in protamine zinc insulin help control the…

A: Biotechnology is the use of our understanding of biological processes to develop useful applications…

Q: Why does von Gierke’s glycogen storage disease cause symptoms of gout?

A: Introduction: Glycogen is the stored energy in the animal's body which is present in the liver. The…

Q: In many individuals with severe cases of A1AT deficiency (the ZZ genotype), intracellular…

A: Alpha-1-Antitrypsin deficiency (AATD) is a genetically inherited autosomal-codominant or autosomal…

Q: What are some advantages, and potential disadvantages, of producing amedicine destined to be…

A: There are various diseases caused due to defective synthesis of proteins. These proteins are…

Q: How does the pathophysiology of diabetes ketoacidosis differ from hyperosmolar non-ketonic coma?

A: Pathophysiology of diabetes ketoacidosis is different from hyersomolar non-ketonic coma. They two…

Q: Describe one mechanism that leads to continued gluconeogenesis in the liver of T1DM patients,…

A: Diabetes mellitus is not a single disorder, it represents a series of metabolic conditions…

Q: What are the main biocheanical role of vitomine B6. of

A: Vitamin B6 is also known as pyridoxine and its active form is paradoxical phosphate.

Q: In humans the purine ring cannot be degraded. How is itexcreted? What reactions are involved?

A: Purine is a heterocyclic aromatic organic compound that consists of two rings. It is water-soluble…

Q: Glucolipids deficiency efects?

A: Glycolipids are those lipid molecules which contain carbohydrates linked through glycosidic…

Q: How will raising the temperature affect the regulation of RodA?   what are the possible results and…

A: Introduction :- Temperature effects different biological processes and structures differently . The…

Q: Why is DNP no longer recommended as a weight-loss aid?

A: Weight loss is a decrease in the weight of the body. Weight loss can be unintentional or…

Q: how does membrane transport maintain glucose level in the cells through the Na+ - K+ pump?

A: Sodium ions are about 14 times more in ecf than in the cytosol similarly the potassium ions are…

Q: What reaction does salivary amylase speed up? How did we test the occurrence of that reaction? What…

A: The salivary glands in the oral cavity secrete saliva which consists of an enzyme such as salivary…

Q: explain why natural protease inhibitors (peptide extracts from the pancreas of cattle - aprotinin)…

A: Enzymes are known as biological catalysts. The function of a catalyst is to accelerate the rate of a…

Q: The trypsin concentration is substantially higher than the inhibitor concentration. What is the…

A: Trypsin is a pancreatic protease which helps in the digestion of proteins. Trypsin is secreted in…

Q: What is diabetic ketoacidosis and how does it happen?

A: A actions of two hormones, insulin and glucagon, control and maintain blood glucose levels in the…

Q: Why isn't the cooking ofvitamin C-containing foodsappropriate for vitamin Csupply?

A: Vitamins are organic molecules and are essential micronutrients that are required in small…

Q: Why is amyloid toxic to cellsand how does it contribute toneurodegenerative diseases such…

A: Pathogenic amyloids formation takes place, when healthy proteins lose their normal structure…

Q: What are the available dosage forms of:1. Acalka®2. Akineton®3. Aldomet®4. Andriol®5. Augmentin®

A: Drug: Any chemical substance that alters physical or emotional changes through its chemical action…

Q: How Is Oxaloacetate Regenerated to Completethe TCA Cycle?

A: The citric acid cycle is a series of chemical reactions which was an aerobic respiration process…

Q: what are the effects of PSTMB shown and why is it important to show effects of PSTMB in vitro…

A: Introduction: According to the Warburg hypothesis, cancer cells undergo a high rate of intracellular…

Q: In what way has the production of human insulin by recombinant DNA methods had significant medical…

A: human insulin is prepared by using two important methods: 1. Semisynthetic human insulin synthesized…

Q: What happened if we add normal saline instead of PBS during beta-amylase extraction?

A: Most enzymes are proteins. Their catalytic activity depends on the integrity of their native…

Q: Over what pH range are trypsin and chymotrypsin active and does this reflect their working…

A:

Q: How is glucose actively transported from gut lumen to gut epithelium even when the concentration of…

A: The mechanism of glucose uptake differs throughout tissues depending upon the metabolic needs of the…

Q: HBA1C control glucose for how much time ? What is the HBA1C criteria for a patient to be diagnosed…

A: Glycated hemoglobin ( HBA1C )  glycates  the amino group of lysyl residues  and  the amino terminals…