You have conducted a simple population genetics analysis of two species. For both species you have measured genotype frequencies at a single locus for 50 individuals sampled from two locations. The data you obtained for each species is shown below Species A - observed genotype frequencies at two sampling locations and for both locations combined HWE expected Genotype heterozygote Allele Frequencies Frequencies frequency Total # A/A A/a a/a Р q 2pq individuals Location 1 10 31 50 0.28 0.72 Location 2 32 6 12 50 0.70 0.30 Location 1 + 41 16 43 100 Location 2 Species B- observed genotype frequencies at two sampling locations and for both locations combined HWE expected Allele heterozygote Genotype Frequencies Frequencies frequency A/A Ala a/a Total р q 2pq Location 1 13 21 16 50 0.47 0.53 Location 2 15 25 10 50 0.55 0.45 Location 1 + 28 46 26 100 Location 2 Hs = expected heterozygosity averaged across all locations HT = expected heterozygosity for the entire population (i.e. location 1 + location 2) FST = 1 - (HS/HT)

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter14: Biotechnology And Society
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You have conducted a simple population genetics analysis of two species. For both
species you have measured genotype frequencies at a single locus for 50 individuals
sampled from two locations. The data you obtained for each species is shown below
Species A - observed genotype frequencies at two sampling locations and for
both locations combined
HWE
expected
Genotype
heterozygote
Allele
Frequencies
Frequencies
frequency
Total #
A/a
a/a
Р
q
2pq
individuals
Location 1
10
31
50
0.28 0.72
Location 2
6
12
50
0.70 0.30
Location 1 +
41
16
43
100
Location 2
Species B - observed genotype frequencies at two sampling locations and for
both locations combined
HWE
expected
Allele
heterozygote
Genotype
Frequencies
Frequencies
frequency
A/A A/a
a/a
Total
Р
2pq
Location 1
13
21
16
50
0.47
0.53
Location 2
15
25
10
50
0.55
0.45
Location 1 +
28
46
26
100
Location 2
Hs = expected heterozygosity averaged across all locations
H₁ = expected heterozygosity for the entire population (i.e. location 1 + location 2)
FST = 1 (HS/HT)
A/A
9
32
Transcribed Image Text:You have conducted a simple population genetics analysis of two species. For both species you have measured genotype frequencies at a single locus for 50 individuals sampled from two locations. The data you obtained for each species is shown below Species A - observed genotype frequencies at two sampling locations and for both locations combined HWE expected Genotype heterozygote Allele Frequencies Frequencies frequency Total # A/a a/a Р q 2pq individuals Location 1 10 31 50 0.28 0.72 Location 2 6 12 50 0.70 0.30 Location 1 + 41 16 43 100 Location 2 Species B - observed genotype frequencies at two sampling locations and for both locations combined HWE expected Allele heterozygote Genotype Frequencies Frequencies frequency A/A A/a a/a Total Р 2pq Location 1 13 21 16 50 0.47 0.53 Location 2 15 25 10 50 0.55 0.45 Location 1 + 28 46 26 100 Location 2 Hs = expected heterozygosity averaged across all locations H₁ = expected heterozygosity for the entire population (i.e. location 1 + location 2) FST = 1 (HS/HT) A/A 9 32
(a) For both Species A and Species B, calculate the observed allele frequencies (p
and q) for Location 1+2 combined, and the expected heterozygote frequencies (2pq,
assuming Hardy-Weinberg equilibrium) for Location 1, Location 2 and Location 1 + 2
(combined).
Provide the HWE expected heterozygote frequencies for:
species A - location 1 =
species A - location 2 =
species A - location 1+2 =
species B - location 1 =
species B - location 2 =
species B - location 1+2=
(b) using the information provided under the tables, calculate FST for each species
Fst species A =
Fst species B =
(c) What do these values for FST tell you about geographic population subdivision in
each species? Briefly explain your reasoning.
Transcribed Image Text:(a) For both Species A and Species B, calculate the observed allele frequencies (p and q) for Location 1+2 combined, and the expected heterozygote frequencies (2pq, assuming Hardy-Weinberg equilibrium) for Location 1, Location 2 and Location 1 + 2 (combined). Provide the HWE expected heterozygote frequencies for: species A - location 1 = species A - location 2 = species A - location 1+2 = species B - location 1 = species B - location 2 = species B - location 1+2= (b) using the information provided under the tables, calculate FST for each species Fst species A = Fst species B = (c) What do these values for FST tell you about geographic population subdivision in each species? Briefly explain your reasoning.
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