Explanation Given information: The initial conditions that are given are The kill curve of ciprofloxacin for E. coli when measured in a growth chamber. A dose corresponding to a concentration of was given at t = 0. Calculation: Together, the antibiotic concentration profile and the dose response relationship determine how the bacteria population size changes over time. When the antibiotic is first administered, the concentration at the site of infection will be high and therefore the growth rate of the bacteria population will be negative (the population will decline). As the antibiotic concentration decays, the growth rate of the bacteria population eventually changes from negative to positive and the bacteria population size then rebounds. The plot of the bacteria population size as a function of time after the antibiotic is given is called the kill curve. An example is shown in Figure.

15th Edition

ISBN: 9781305177291

Author: James Stewart, Troy Day

Publisher: Cengage Learning

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Chapter 1, Problem 1CS

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To calculate: description and comments on the characteristics of the predicted curve shown in the figure.

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Chapter 1, Problem 40E

Chapter 1, Problem 2CS

Chapter 1 Solutions

Biocalculus: Calculus For Life Sciences

Ch. 1.1 - Prob. 1E Ch. 1.1 - Prob. 2E Ch. 1.1 - Prob. 3E Ch. 1.1 - Prob. 4E Ch. 1.1 - Prob. 5E Ch. 1.1 - Prob. 6E Ch. 1.1 - Prob. 7E Ch. 1.1 - Prob. 8E Ch. 1.1 - Prob. 9E Ch. 1.1 - Prob. 10E

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description and comments on the characteristics of the predicted curve shown in the figure.

Solution Summary: The author explains how clinical researchers measure kill curves for different antibiotic doses to determine how much antibiotic should be used to treat an infection.

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To calculate: description and comments on the characteristics of the predicted curve shown in the figure.

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Chapter 1 Solutions