A patient, age 10 years diagnosed earlier with Wilson's disease, reported with giardiasis at the emergency room. Characters in the case: Richard Brennan, the patient under evaluation. Adequate information: The patient was being treated with penicillamine for Wilson's disease. During the treatment, he has reported of multiple sinus infections, one instance of pneumonia and now giardiasis. Blood investigations reveal normal B and T cell counts, normal IgG and IgM but very low IgA compared to reference levels. His case was assessed as that of the drug-induced transient form of IgA deficiency attributed to the use of penicillamine in Wilson's disease. To Determine: The nature of antibodies that use the same transport receptors as dimeric IgA that would have been present in the lumen of GI tract and mucosal secretions of Richard while he was taking penicillamine.

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Answer 1

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 10, Problem 15Q

Summary Introduction

Case summary:

A patient, age 10 years diagnosed earlier with Wilson's disease, reported with giardiasis at the emergency room.

Characters in the case:

Richard Brennan, the patient under evaluation.

Adequate information:

The patient was being treated with penicillamine for Wilson's disease. During the treatment, he has reported of multiple sinus infections, one instance of pneumonia and now giardiasis. Blood investigations reveal normal B and T cell counts, normal IgG and IgM but very low IgA compared to reference levels. His case was assessed as that of the drug-induced transient form of IgA deficiency attributed to the use of penicillamine in Wilson's disease.

To Determine:

The nature of antibodies that use the same transport receptors as dimeric IgA that would have been present in the lumen of GI tract and mucosal secretions of Richard while he was taking penicillamine.

Expert Solution & Answer

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Answer 2

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 10, Problem 15Q

Summary Introduction

Case summary:

A patient, age 10 years diagnosed earlier with Wilson's disease, reported with giardiasis at the emergency room.

Characters in the case:

Richard Brennan, the patient under evaluation.

Adequate information:

The patient was being treated with penicillamine for Wilson's disease. During the treatment, he has reported of multiple sinus infections, one instance of pneumonia and now giardiasis. Blood investigations reveal normal B and T cell counts, normal IgG and IgM but very low IgA compared to reference levels. His case was assessed as that of the drug-induced transient form of IgA deficiency attributed to the use of penicillamine in Wilson's disease.

To Determine:

The nature of antibodies that use the same transport receptors as dimeric IgA that would have been present in the lumen of GI tract and mucosal secretions of Richard while he was taking penicillamine.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 10, Problem 15Q

Summary Introduction

Case summary:

A patient, age 10 years diagnosed earlier with Wilson's disease, reported with giardiasis at the emergency room.

Characters in the case:

Richard Brennan, the patient under evaluation.

Adequate information:

The patient was being treated with penicillamine for Wilson's disease. During the treatment, he has reported of multiple sinus infections, one instance of pneumonia and now giardiasis. Blood investigations reveal normal B and T cell counts, normal IgG and IgM but very low IgA compared to reference levels. His case was assessed as that of the drug-induced transient form of IgA deficiency attributed to the use of penicillamine in Wilson's disease.

To Determine:

The nature of antibodies that use the same transport receptors as dimeric IgA that would have been present in the lumen of GI tract and mucosal secretions of Richard while he was taking penicillamine.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 10, Problem 15Q

Summary Introduction