EBK HUMAN ANATOMY
9th Edition
ISBN: 9780135241752
Author: Marieb
Publisher: PEARSON CO
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Chapter 10, Problem 4CRCAQ
Takashi, an osteopathic physician, saw that Mrs. and Mr. Rogers were suffering because their son was fighting a long battle with Duchenne muscular dystrophy. To comfort them, Takashi said that one day physicians hope to be able to cure this disease by injecting healthy myoblasts into the weakened muscles. What are myoblasts?
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2) Paula is a scientist who is developing a drug called Fremtol that will be used to treat muscle spasms. This drug acts on specific skeletal muscles to (1) block the release of Ca2+ ions from the sarcoplasmic reticulum, (2) inhibit the pivoting ability of the myosin heads of the thick filaments, and (3) block the production of ATP by the mitochondria in skeletal muscles. By using this drug, contraction of certain skeletal muscle fibers is reduced, which keeps those muscles from producing spasms.
In the above scenario, Fremtol’s effect of blocking the release of Ca2+ ions from the sarcoplasmic reticulum would most directly prevent which the following?
a. activation of tropomyosin
b. activation of troponin
c. activation of actin
d. All of the above
e. None of the above
3) Paula is a scientist who is developing a drug called Fremtol that will be used to treat muscle spasms. This drug acts on specific skeletal muscles to (1) block the release of Ca2+ ions from the sarcoplasmic reticulum, (2) inhibit the pivoting ability of the myosin heads of the thick filaments, and (3) block the production of ATP by the mitochondria in skeletal muscles. By using this drug, contraction of certain skeletal muscle fibers is reduced, which keeps those muscles from producing spasms.
In the above scenario, Fremtol’s effect of blocking muscle mitochondrial ATP production would result in the inability of the muscle to make ATP from ___________.
a. creatine phosphate
b. anaerobic glycolysis
c. aerobic respiration
d. All of the above
e. None of the above
Please answer all questions
Following death, muscles enter a period of sustained contraction called rigor mortis. This develops because:
a) the Na+/K+ active transport pump fails.
b) there isn't any more neurotransmitter secretion.
c) there isn't any ATP to break actin-myosin bonds.
d) calcium is not returned to the cisternae.
If a muscle is stimulated to contract at maximum tension yet brief periods of relaxation are possible, the muscle is demonstrating:
a) twitch.
b) summation.
c) incomplete tetany.
d) complete tetany.
Chapter 10 Solutions
EBK HUMAN ANATOMY
Ch. 10 - What structural similarities are shared by all...Ch. 10 - Prob. 2CYUCh. 10 - Prob. 3CYUCh. 10 - What are the functional definitions of the origin...Ch. 10 - Place the following structures in order from...Ch. 10 - Which myofilaments are found only in the A band?Ch. 10 - Prob. 7CYUCh. 10 - Prob. 8CYUCh. 10 - Prob. 9CYUCh. 10 - Prob. 10CYU
Ch. 10 - Prob. 11CYUCh. 10 - Prob. 12CYUCh. 10 - Prob. 13CYUCh. 10 - Prob. 14CYUCh. 10 - The connective tissue that lies just outside the...Ch. 10 - Prob. 2RQCh. 10 - Prob. 3RQCh. 10 - Prob. 4RQCh. 10 - Prob. 5RQCh. 10 - Prob. 6RQCh. 10 - Prob. 7RQCh. 10 - Prob. 8RQCh. 10 - Prob. 9RQCh. 10 - Prob. 10RQCh. 10 - Prob. 11RQCh. 10 - Prob. 12RQCh. 10 - Define motor unit.Ch. 10 - List the structural differences between the three...Ch. 10 - Cindy Wong was a good anatomy student, but she...Ch. 10 - Prob. 16RQCh. 10 - Prob. 17RQCh. 10 - Where is titin located, and what are its...Ch. 10 - What is the general distribution of skeletal...Ch. 10 - Prob. 1CRCAQCh. 10 - Prob. 2CRCAQCh. 10 - Chickens are capable of only brief bursts of...Ch. 10 - Takashi, an osteopathic physician, saw that Mrs....Ch. 10 - Why are muscle infections relatively rare...Ch. 10 - As a sprinter, Lateesha knew that the best way to...Ch. 10 - Prob. 7CRCAQCh. 10 - Prob. 8CRCAQCh. 10 - Prob. 9CRCAQ
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A) tetany is rapid spasm in the muscle. B) Tetany is usually caused by an increase in the blood calcium levels. Write whether statement (B) is correct w.r.t statement (A) ?arrow_forwardHow does Muscular dystrophy disease affect a common human being?arrow_forwardTroponin C has been mutated such that it cannot bind to calcium. Describe the effect of this mutation on sarcomere shortening in skeletal muscle. A complete answer will describe the normal function of troponin C, the normal process of sarcomere shortening, and will describe the overall effect of the mutation on sarcomere shortening based on troponin C's function and its role in the overall process of sarcomere shortening.arrow_forward
- An increase in the cross sectional area of muscle is known as hypertrophy. Hypertrophy allows muscle to produce more force due primarily to: a.) Increased number of potential cross bridges that can be formed (i.e., actin-myosin interactions) b.) Increased number of T-Tubules c.) Increased ability to activate the muscle d.) Increased calcium release from the sarcoplasmic reticulumarrow_forward15) what role does calcium play in muscle contraction? a) calcium is not involved in skeletal muscle contraction b) it binds to tropomyosin and moves Tripp in away from the myosin binding sit on the actin molecules c) it's binds to Troponin and moves tropomyosin away from the actin binding sit on the myosin molecules d) it binds to troponin and moves tropomyosin away from the myosin binding site on the actin molearrow_forwardWith muscular dystrophy, the membrane of muscle cells is destroyed. Given how muscle cells contract, which of the following would fail to happen? Reuptake of acetylcholine by the muscle cells ) Reuptake of acetylcholine by lower motor neurons ) Action potential conduction on muscle cells Action potential conduction on the lower motor neuronsarrow_forward
- A woman is having an extremely prolonged labor. From her anatomy andphysiology course, she remembers the role of Ca2+ in muscle contractionand asks the doctor to give her a Ca2+ injection to speed the delivery.Explain why the doctor would or would not do as she requests.arrow_forwardAt first, Donnie’s wife accused her once-active 25-year-old husbandof trying to get out of housework by constantly complaining aboutpain and stiffness in his lower back. But over the next 5 months, thepain and stiffness increased and seemed to be spreading up his vertebral column. The family doctor referred Donnie to a rheumatologist,who diagnosed ankylosing spondylitis (AS). AS, a chronic inflammation of joints at points where ligaments, tendons, and joint capsuleinsert into bone, causes fibrosis (the development of scar tissue), ossification, and fusion of joints. Combine your knowledge about bonegrowth, repair, and anatomy from chapters 6 and 7 and joint structureand function from this chapter to identify the category of joints primarily affected by AS, and explain how chronic inflammation ofDonnie’s joints led to their fusion.arrow_forwardHello, may I please get help with this physiology question? An explanation leading to the correct answer would be helpful! Scenario: Your friend Arnold S, who sometimes goes by "Dutch", has started lifting weights because he wants his muscles to get bigger. He's done a little bit of research, and he tells you that weight lifting is increasing the size of myofibrils. Arnie is getting huge, and so you are hesitant to correct him, but you know that what he's saying isn't quite right. The more likely explanation for Arnold's muscles getting bigger is...arrow_forward
- Muscular strength is defined as the: a) ability of a muscle to contract with maximal force O b) ability to move the joints through a full range of motion O c) ability to sustain a given level of muscular tension over time d) amount of force a muscle can produce repeatedly over 60 secondsarrow_forwardMuscular endurance is defined as the: O a) ability of a muscle to contract repeatedly over an extended period of time b) amount of force a muscle can produce with a single maximal effort O c) ability to move the joints through a full range of motion O d) amount of time required to contract a muscle completelyarrow_forwardWhich of the following step(s) about the excitation of skeletal muscle is/are incorrect? 1. Acetylcholine is released and binds to motor end plate receptors 2. An action potential is created and moves down T-tubules 3. Calcium is released from the sarcoplasmic reticulum 4. Calcium ions bind to tropomyosin to shift troponin off the binding sites for cross-bridging 5. Myosin forms cross-bridges and binds with actin to pull it towards middle of sarcomerearrow_forward
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